TY - JOUR AU - Toro-Salazar, Olga H. AU - Gillan, Eileen AU - Ferranti, Joanna AU - Orsey, Andrea AU - Rubin, Karen AU - Upadhyay, Shailendra AU - Mazur, Wojciech AU - Hor, Kan N. PY - 2015 DA - 2015/11/26 TI - Effect of myocardial dysfunction in cardiac morbidity and all cause mortality in childhood cancer subjects treated with anthracycline therapy JO - Cardio-Oncology SP - 1 VL - 1 IS - 1 AB - Subacute cardiotoxicity, consisting of acute myocyte damage and associated left ventricular dysfunction, occurs early during anthracycline therapy. We investigated the impact of myocardial dysfunction, defined herein by a shortening fraction (SF) < 29 % at any time during or after anthracycline therapy, on late onset cardiomyopathy and all-cause mortality, among childhood cancer survivors exposed to anthracyclines. In addition, we sought to identify subpopulations of subjects at highest risk for cardiomyopathy and death from all causes. SN - 2057-3804 UR - https://doi.org/10.1186/s40959-015-0005-8 DO - 10.1186/s40959-015-0005-8 ID - Toro-Salazar2015 ER -