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Table 3 Kidney pathology scores in WKY rats based on evaluation of hematoxylin and eosin (HE) stained sections

From: The interplay between genetic background and sexual dimorphism of doxorubicin-induced cardiotoxicity

Sex

Treatment

Glomerular lesions score

Tubular lesions score

Interstitial inflammation and fibrosis score

Cumulative kidney score

Male

Saline

0 (0–0)

0 (0–0)

0 (0–0)

0 (0–0)

 

DOX

2 (1–2)*

2 (1–3)*

2 (1–2)*

6 (3–7)*

Female

Saline

0 (0–0)

0 (0–0)

0 (0–0)

0 (0–0)

 

DOX

1 (0–1)

1 (0–1)

0 (0–0)#

2 (0–2)

  1. Data are presented as the median and 95 % confidence interval of the median
  2. *p < 0.05 significantly different from Saline group of the same sex
  3. #p < 0.05 significantly different from males within the same treatment group