Table 4 Kidney pathology scores in SHHF rats based on evaluation of hematoxylin and eosin (HE) stained sections
From: The interplay between genetic background and sexual dimorphism of doxorubicin-induced cardiotoxicity
Sex | Treatment | Glomerular lesions score | Tubular lesions score | Interstitial inflammation and fibrosis score | Cumulative kidney score |
|---|---|---|---|---|---|
Male | Saline | 0 (0–0) | 0 (0–0) | 0 (0–0) | 0 (0–0) |
|  | DOX | 4 (3–4)* | 4 (3–4)* | 3 (3–4)* | 11 (9–12)* |
Female | Saline | 0 (0–0) | 0 (0–0) | 0 (0–0) | 0 (0–0) |
|  | DOX | 2 (1–3) | 2 (2–3) | 2 (2–3) | 6 (5–9) |