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Fig. 5 | Cardio-Oncology

Fig. 5

From: Recurrent heart failure with preserved ejection fraction associated with carfilzomib administration for multiple myeloma

Fig. 5

Pressure waveforms measured in the left ventricle during left cardiac catheterization with a 5 French pigtail catheter. Procedure was performed 1 day after the first treatment on the 9th cycle of carfilzomib administration. Panel (a): Measurements obtained prior to left ventriculography with an end expiratory left ventricular end diastolic pressure (LVEDP) of approximately 18 mmHg, and a left ventricular systolic pressure was approximately 134 mmHg. Panel (b): Measurements obtained immediately after 20 cm3 of iodinated contrast of left ventriculography with an increase of the LVEDP to 22 mmHg, with a left ventricular systolic pressure of 142 mmHg. LV ejection fraction was approximately visualized at 50–55% but hampered by significant ventricular ectopy during ventriculography. BNP level measured after procedure was elevated at 288 pg/ml

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