| |
Study group (n = 13) Median (25–75% range) or n (%)
|
Subjects who withdrew (n = 7) Median (25–75% range) or n (%)
|
p
|
Control group (n = 62) Median (25–75% range) or n (%)
|
p
|
|---|
|
Age at diagnosis
|
15.7 (13.4–17.7)
|
15 (12–16.1)
|
.60
|
17 (13–27)
|
.28
|
|
Female
|
8 (61.5)
|
2 (28.6)
|
.35
|
32 (53.3)
|
.56
|
|
Total cumulative anthracyclines (g/m2)
|
200 (158–200)
|
NA
| |
NA
| |
|
Vinca Alkaloids
|
9 (69.2)
|
NA
| |
NA
| |
|
Previous bone marrow transplant
|
0 (0)
|
NA
| |
NA
| |
|
Previous heart disease
|
3 (23.1)
|
NA
| |
NA
| |
|
Height (cm)
|
161 (153–170.2)
|
NA
| |
NA
| |
|
Weight (kg)
|
54 (40–84.8)
|
NA
| |
NA
| |
|
BMI (kg/m2)
|
20.6 (17.9–22)
|
NA
| |
NA
| |
|
Systolic pressure (mmHg)
|
108 (106–117)
|
NA
| |
NA
| |
|
Diastolic pressure (mmHg)
|
64 (55–66)
|
NA
| |
NA
| |
|
Number of transfusions (n = 11)
|
10 (0–49)
|
NA
| |
NA
| |
|
Cancer Diagnosis
| | |
.03
|
NA
| |
|
ALL
|
4 (30.8)
|
0 (0)
| |
NA
| |
|
Hodgkin’s Lymphoma
|
6 (46.2)
|
1 (14.3)
| |
NA
| |
|
AML
|
1 (7.7)
|
2 (28.6)
| |
NA
| |
|
Osteosarcoma
|
2 (15.4)
|
1 (14.3)
| |
NA
| |
|
Other
|
0 (0)
|
3 (42.9)
| |
NA
| |
- n number of subjects, SD standard deviation, BMI body mass index, ALL acute lymphoblastic leukemia, AML acute myeloblastic leukemia
- All p-values are compared to the study group (n = 13) only
