Table 2 Adverse Events
CTCAE Term | # Patients (% Patients) Doxorubicin/Sildenafil N = 10 | |||
|---|---|---|---|---|
Grade1 | Grade2 | Grade3 | Grade4 | |
Alanine aminotransferase increased | 1 (10) | |||
Alkaline phosphatase increased | 1 (10) | |||
Alopecia | 3 (30) | |||
Anemia | 1 (10) | 3 (30) | 1 (10) | |
Anorexia | 2 (20) | 1 (10) | ||
Constipation | 2 (20) | |||
Creatinine increased | 1 (10) | |||
Dry eye | 1 (10) | |||
Dysgeusia | 2 (20) | |||
Dyspepsia | 2 (20) | 2 (20) | ||
Edema limbs | 1 (10) | |||
Ejection fraction decreased | 3 (30) | |||
Eye disorders | 3 (30) | |||
Fatigue | 3 (30) | 3 (30) | ||
Fever | 1 (10) | |||
Flushing | 2 (20) | |||
Genital edema | 1 (10) | |||
Headache | 3 (30) | 1 (10) | 2 (20) | |
Hypocalcemia | 2 (20) | |||
Hypokalemia | 2 (20) | |||
Hypophosphatemia | 1 (10) | |||
Investigations - Other, specify | 1 (10) | |||
Left ventricular systolic dysfunction | 1 (10) | |||
Lip infection | 1 (10) | |||
Lymphocyte count decreased | 2 (20) | 1 (10) | 1 (10) | |
Mucositis oral | 1 (10) | 1 (10) | 1 (10) | |
Nail discoloration | 1 (10) | |||
Nausea | 5 (50) | 2 (20) | ||
Peripheral sensory neuropathy | 1 (10) | 1 (10) | ||
Platelet count decreased | 4 (40) | |||
Skin infection | 1 (10) | |||
Vomiting | 1 (10) | |||