Table 1 Demographic, clinical, and vascular parameters

 Age (years)

25.0 ± 5.9

23.6 ± 5.8

0.16

 Sex (M/F)

54/42

30/30

0.45

 Weight (kg)

59.1 ± 10.8

59.2 ± 11.0

0.97

 Height (cm)

166.1 ± 8.7

165.9 ± 8.6

0.85

 Body mass index (kg/m²)

21.4 ± 3.2

21.4 ± 2.6

0.99

 Age at diagnosis (years)

 Duration since completion of therapy (years)

 Cumulative anthracycline dose (mg/m²)

 Acute lymphoblastic leukaemia

50

 Non-Hodgkin lymphoma

15

 Acute myeloid leukaemia

10

 Osteosarcoma

4

 Hodgkin lymphoma

5

 Wilm’s tumour

6

 Ewing Sarcoma

2

 Clear cell sarcoma of kidney

1

 Ganglioneuroblastoma

1

 Neuroblastoma

1

 Peripheral primitive neuroectodermal tumour

1

Need for cardiac irradiation

5

Relapse

9

Cardiac medication

0

  IMT (mm)

0.44 ± 0.03

0.41 ± 0.02

< 0.001

  Stiffness index

4.05 ± 0.02

3.85 ± 0.61

< 0.001

  Pulse pressure (mmHg)

42 ± 8

43 ± 9

0.34

  cSBP (mmHg)

111 ± 16

105 ± 16

0.037

  rAI (%)

64 ± 15

57 ± 13

0.004

  rAI at 75 beats/min (%)

64 ± 14

58 ± 12

0.009