Table 1 Design of all three studies
From: Systemic and cardiac susceptibility of immune compromised mice to doxorubicin
| Study | Weekly Doxorubicin Dose | Cumulative Doxorubicin Dose | # Saline Mice | # Doxorubicin Mice |
|---|---|---|---|---|
| I | 4 mg/kg | 8 mg/kg | 14 (7♀, 7♂) | 14 (7♀, 7♂) |
| II | Dose escalation: 0.5 mg/kg with weekly increases by 0.5 mg/kg | 5 mg/kg | N/A | 5 (3♂, 2♀) |
| III | 0.5 mg/kg | 3 mg/kg | 4 (2♀, 2♂) | 4 (2♀, 2♂) |