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Table 1 Design of all three studies

From: Systemic and cardiac susceptibility of immune compromised mice to doxorubicin

Study

Weekly Doxorubicin Dose

Cumulative Doxorubicin Dose

# Saline Mice

# Doxorubicin Mice

I

4 mg/kg

8 mg/kg

14 (7♀, 7♂)

14 (7♀, 7♂)

II

Dose escalation: 0.5 mg/kg with weekly increases by 0.5 mg/kg

5 mg/kg

N/A

5 (3♂, 2♀)

III

0.5 mg/kg

3 mg/kg

4 (2♀, 2♂)

4 (2♀, 2♂)