Skip to main content

Table 3 Reported nadir LVEF, wall motion abnormalities, follow-up LVEF, and patient outcome

From: Takotsubo cardiomyopathy in cancer patients

Reference No.

Nadir LVEF (%)

LV Wall Motion Abnormality

Coronary Angiogram

Followup LVEF (At Interval)

Outcome

[18]

15–20%

Severe global hypokinesis with apical ballooning in systole and diastole

non-obstructive CAD

55–60% (4 weeks)

Survived

[19]

28%

Extensive apical akinesis

normal coronary arteries

67% (10 days)

Survived

[20]

15%

Severe diffuse hypokinesis

N/A

40–45% (10 days), 60% (3 months)

Survived

[21]

20%

N/A

N/A

60% (N/A)

Survived

[17]

30%

No regional wall motion abnormality

normal coronary arteries

55–65% (2 months)

Survived

[22]

15%

Severe hypokinesia in all apical and mid segments, normokinetic basal wall

N/A

30% (1 day), 55–65% (5 days)

Survived

[23]

10% (Cardiac Arrest)

Global Hypokinesia

non-obstructive CAD

68% (4 weeks)

Survived

[24]

15%

Hypokinesis of mid-apical and hyperkinesis of basal segments

non-obstructive CAD

50% (4 weeks)

Deceased (Progression of Cancer)

[25]

20%

N/A

N/A

EF recovered (2 weeks)

Deceased (Cardiac Asystole during 5th cycle of 5FU)

[26]

34%

Apical and periapical akinesia

non-obstructive CAD

70% (4 weeks)

Survived

[20]

35%

Akinesis of the distal half of the anterior and inferior walls not consistent with a single vascular territory

non-obstructive CAD

60% (4 weeks)

Survived

[27]

30%

Anteroapical wall motion abnormality

non-obstructive CAD

55% (6 weeks)

Survived

[28]

15–20%

Hypokinetic basal segment

Atheromatous changes with markedly sluggish blood flow in LAD

55% (1 week)

Survived

[29]

35%

Extensive anterior wall hypokinesis inconsistent with a single coronary artery territory

non-obstructive CAD

55–65% (1 week)

Survived

[30]

28%

N/A

N/A

62% (1 week)

Survived

[31]

N/A

Apical akinesis and a hyperdynamic basal segment

N/A

Normal (3 weeks)

Survived

[31]

N/A

N/A

non-obstructive CAD

Recovered (2 weeks)

Survived

[32]

40–50%

Apical akinesis

non-obstructive CAD

55–65% (4 weeks)

Survived

 

50–55%

Apical/Septal hypokinesis

N/A

60–65% (4 weeks)

Survived

[33]

40%

Hypokinesis of the anterior wall

non-obstructive CAD

N/A

Death due to pathological fracture (unrelated to cardiomyopathy)

[34]

15–20%

Global hypokinesis with apical ballooning in systole and diastole

non-obstructive CAD

68% (3 months)

Survived

[35]

20–25%

Severe global hypokinesis with anterior apical ballooning

non-obstructive CAD

50–55% (3 weeks)

Survived

[36]

N/A

Systolic bulge at mid-LV with normal apical and basal segments

normal coronary arteries

Normal (6 weeks)

Survived

[37]

30–35%

Segmental wall motion abnormalities: mild anterior, septal, apical, inferior and lateral wall hypokinesia

non-obstructive CAD

50% (2 weeks)

Survived

[38]

50%

Akinetic apex, hyperkinetic base and septum

non-obstructive CAD

N/A

Survived