Table 1 Baseline characteristics
Left/Bilateral TE | Right/No recontstruction TE | p value* | |||
|---|---|---|---|---|---|
Race | 0.738 | ||||
Non-white | (6) | 18.7% | (37) | 23.4% | |
White | (26) | 81.3% | (121) | 76.6% | |
Age at dx | 48 ± 12.4 | 57.5 ± 11.1 | 0.000 | ||
Breast Cancer | |||||
Primary side | |||||
Right | (9) | 28.2% | (74) | 46.8% | |
Left | (23) | 71.8% | (79) | 50% | |
Bilateral | (1) | 2% | (5) | 3.2% | |
Size | 0.010 | ||||
2–5 cm | (8) | 25% | (40) | 25.3% | |
> 5 cm | (5) | 15.6% | (6) | 3.7% | |
Chest or skin invasion | (1) | 3.2% | (1) | 0.6% | |
Not specified | (1) | 3.2% | (9) | 5.6% | |
Node status | 0.329 | ||||
N0 | (14) | 43.7% | (83) | 52.5% | |
N1 | (18) | 56.3% | (73) | 46.2% | |
Grade | 0.633 | ||||
I | (3) | 9.4% | (22) | 14.2% | |
II | (18) | 25% | (41) | 26.5% | |
III | (16) | 50% | (56) | 36.1% | |
Not specified | (7) | 15.6% | (36) | 23.2% | |
TE side | |||||
Left | (14) | 7.4% | |||
Right | (7) | 3.4% | |||
Bilateral | (18) | 9.4% | |||
No reconstruction | (151) | 79.4% | |||
Treatment | |||||
Anthracyclines | (28) | 90.2% | (104) | 70.7% | 0.049 |
Antiestrogen | (25) | 78.1% | (100) | 68% | 0.248 |
Trastuzumab | (29) | 90.6% | (105) | 70.9% | 0.012 |
Radiation Therapy | (29) | 90.6% | (104) | 71.2% | 0.001 |
ECHO | |||||
LVEF | 58 ± 5 | 58 ± 7 | 0.913 | ||
BMI | 26.9 ± 5.4 | 28.7 ± 7.3 | 0.242 | ||
SBP | 123 ± 18 | 131 ± 22 | 0.051 | ||
DBP | 71 ± 10 | 73 ± 12 | 0.350 | ||
Comorbidities | |||||
COPD | – | (8) | 5% | 0.016 | |
Prior Chest surgery | (3) | 9.7% | (13) | 8.4% | 0.826 |
HTN | (16) | 51.6% | (87) | 56.5% | 0.618 |
DM | (3) | 9.4% | (25) | 16.2% | 0.300 |
Dyslipidemia | (8) | 25% | (49) | 32% | 0.427 |
Heart failure | (2) | 6.5% | (17) | 11% | 0.419 |
CKD | (1) | 3.2% | (4) | 2.6% | 0.852 |
CAD | (1) | 3.2% | (17) | 11% | 0.278 |
Obesity | (17) | 32.7% | (73) | 36.9% | 0.879 |
Medications | |||||
ASA | (7) | 21.9% | (45) | 29.2% | 0.390 |
ACE/ARB | (8) | 25% | (38) | 24.7% | 0.969 |
Beta blocker | (8) | 25% | (47) | 30.5% | 0.528 |
Statin | (9) | 28.1% | (44) | 28.8% | 0.942 |
Smoking | 0.615 | ||||
Never smoker | (16) | 53.3% | (80) | 57.6% | |
Former Smoker | (11) | 36.7% | (52) | 37.4% | |
Active Smoker | (3) | 10% | (7) | 5.9% | |