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Table 3 Dosimetric data evaluating LGE

From: Cardiac MRI utilizing late gadolinium enhancement (LGE) and T1 mapping in the detection of radiation induced heart disease

Factor (mean (range))

All patients (N = 28)

No LGE (N = 19)

LGE (N = 9)

p-value

Dmax Heart EQD2 (Gy)

50.9 (6.2–108.0)

46.1 (6.2–82.6)

60.8 (40.8–108.0)

0.16

Dmean Heart EQD2 (Gy)

8.2 (1.0–35.7)

8.8 (1.0–35.7)

6.8 (1.8–21.8)

0.57

Dmax LV EQD2 (Gy)

34.0 (0.2–94.7)

29.4 (0.2–74.7)

43.8 (13.6–94.7)

0.17

Dmean LV EQD2 (Gy)

8.2 (0.1–34.4)

8.4 (0.1–30.0)

7.6 (1.4–34.4)

0.84

Heart V5Gy (%)

48.5 (10–97)

49.3 (10–97)

46.8 (13–96)

0.85

Heart V30Gy (%)

10.8 (0–69)

11.0 (0–66)

10.5 (0–44)

0.94

Heart V40Gy (%)

7.6 (0–66)

8.1 (0–66)

6.7 (0–33)

0.83

Heart V50Gy (%)

5.1 (0–59)

5.8 (0–59.0)

3.4 (0–23)

0.65

LV V5Gy (%)

40.1 (0–100)

37.3 (0–100)

45.1 (18.5–100)

0.61

LV V30Gy (%)

10.7 (0–71.8)

10.7 (0–65.1)

10.7 (0–71.8)

0.99

LV V40Gy (%)

7.7 (0–55.5)

7.8 (0–55.5)

7.4 (0–53.1)

0.95

LV V50Gy (%)

5.1 (0–48.8)

5.6 (0–48.8)

4.3 (0–36.4)

0.81

T1 mapping values (ms)

1009 (933–1117)

997 (933–1067)

1033 (967–1117)

0.054

  1. *Dmax maximum dose, Dmean mean dose, EQD2 equivalent dose in 2 Gy fractions, Gy Gray, LGE late gadolinium enhancement, LV left ventricle, ms milliseconds, Vx volume in % receiving ≥ dose x in Gy. P-values reported for significance testing among patients with and without LGE