Table 3 Echocardiographic parameters pre- and post-doxorubicin therapy for cumulative doxorubicin dose < 200 and ≥ 200 mg m− 2
Cumulative Doxorubicin dose (< 200 mg m− 2) | Cumulative Doxorubicin dose (≥200 mg m− 2) | |||||
|---|---|---|---|---|---|---|
Pre | Post | P-value | Pre | Post | P-value | |
LVEF (%) | 63.8 ± 6.9 | 62.9 ± 7.5 | 0.74 | 63.0 ± 5.9 | 60.7 ± 13.1 | 0.34 |
RV GLS | −22.6 ± 3.6 | −21.3 ± 3.9 | 0.32 | −22.3 ± 4.5 | − 20.1 ± 2.9 | 0.03 |
RV FAC | 47.9 ± 4.1 | 46.1 ± 3.9 | 0.18 | 47.0 ± 4.7 | 42.2 ± 3.1 | 0.01 |
RV FWS | −25.2 ± 2.8 | −23.6 ± 3.4 | 0.13 | −24.6 ± 3.6 | −21.5 ± 2.4 | 0.01 |