Resistance to antihypertensive drugs targeting Renin-Angiotensin-Aldosterone-System in cancer patients: a case series

Table 1 Baseline Characteristics of the Series Patients

Case	Age	Gender	Ethnicity	Cancer Type	Chemotherapy/ Radiotherapy	Initial BP Range^a	Final BP Range^b
1.	77	Female	African- American	Multiple Myeloma	Bortezomib	180–190/ 70–80	125–135/ 60–65
2.	85	Male	Caucasian	Prostate Cancer with multiple bone metastasis	Androgen deprivation therapy, External beam radiation therapy	140–150/ 70–80	125–135/ 70–80
3.	79	Female	Caucasian	Ovarian carcino- sarcoma	Bevacizumab	160–180/ 70–80	120–130/ 60–80
4.	65	Female	Caucasian	Ovarian cancer with metastasis	Bevacizumab and cyclophosphamide	160–170/ 90–100	120–140/ 80–90
5.	72	Female	Caucasian	Breast cancer	Trastuzumab	190–210/ 80–90	110–120/ 56–74

^a Range of home blood pressure readings/log at presentation
^b Final BP means range of home blood pressure readings/log when taken off ACEi and/or ARB
Abbreviations: ACEi Ace inhibitor, ARB Angiotensin receptor blocker

ISSN: 2057-3804