Table 1 Characteristics of study participants

Male

68 (74)

38 (78)

30 (70)

Body Mass Index (kg/m²)

24.5 (4.5)

24.8 (4.5)

24.1 (4.5)

0.422

Body Surface Area (m²)

1.9 (0.2)

1.9 (0.2)

1.9 (0.2)

0.536

Age at start cancer therapy (years)

48.2 (18.1)

52.2 (15.8)

43.7 (19.2)

0.024

Age at diagnosis ACD (years)

51.6 (16.2)

52.4 (16.1)

50.8 (16.2)

0.646

 Hematological

86 (94)

48 (98)

38 (88)

 Acute leukemia

44 (51)

32 (67)

12 (32)

 Non-Hodgkin’s lymphoma

6 (7)

1 (2)

5 (13)

 Hodgkin’s lymphoma

26 (30)

8 (17)

18 (47)

 Other^a

10 (12)

7 (15)

3 (8)

 Breast cancer

2 (2)

0 (0)

2 (5)

 Other solid tumors^b

4 (4)

1 (2)

3 (7)

 Cumulative anthracycline dose (mg/m²), [IQR]

329 [200–329]

329 [180–329]

308 [200–400]

0.114

 Chest radiation

7 (8)

1 (2)

6 (14)

 NYHA class I + II

86 (94)

47 (96)

39 (91)

 NYHA class III + IV

6 (6)

2 (4)

4 (9)

  Sinus rhythm

90 (98)

48 (98)

42 (98)

  Atrial fibrillation

2 (2)

1 (2)

1 (2)

  Heart axis

  Normal

82 (89)

42 (86)

40 (93)

  Left

8 (9)

5 (10)

3 (7)

 Right

2 (2)

2 (4)

0 (0)

  Normal

86 (93)

45 (92)

41 (95)

  Left bundle branch block

4 (4)

2 (4)

2 (5)

  Right bundle branch block

2 (2)

2 (4)

0 (0)

 Hypertension

19 (21)

7 (14)

12 (28)

 Diabetes Mellitus

9 (10)

3 (6)

6 (14)

 Hyperlipidemia^c

12 (17)

5 (13)

7 (19)

 Smoking status

n = 80

n = 42

n = 38

 Former smoker

31 (39)

24 (57)

7 (18)

 Current smoker

13 (16)

6 (14)

7 (18)

 Never smoked

36 (45)

12 (29)

24 (64)

 Coronary / Peripheral Artery disease

13 (14)

8 (17)

5 (12)