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Table 1 Comparison of Reynolds risk score variables between exercise and usual care groups

From: Aerobic and resistance exercise improves Reynolds risk score in overweight or obese breast cancer survivors

Variable Baseline, mean (SD) Post-intervention Between Group Difference Post intervention
Mean (SD) Mean (SD) P * Mean (95% CI) P
Age (yrs)
 Exercise 52.8 (10.6); (n = 50) 52.8 (10.6); (n = 48)
 Usual Care 53.6 (10.1); (n = 50) 53.6 (10.1); (n = 45)    
Systolic blood pressure (mmHg)      
 Exercise 132.9 (13.0) 120.7 (9.5) < 0.001* −13.7 (− 16.5 to − 8.7) < 0.001
 Usual Care 133.7 (9.7) 135.9 (9.8) 0.22   
hsCRP (mg/L)
 Exercise 3.4 (0.6) 2.3 (0.3) < 0.001* −1.9 (− 5.2 to − 0.6) < 0.001
 Usual Care 3.7 (0.3) 4.2 (0.4) 0.54   
Total Cholesterol (mg/dL)
 Exercise 196.5 (53.4) 157.5 (37.1) < 0.001* −52.9 (−75.0 to −43.0) < 0.001
 Usual Care 194.4 (48.9) 210.4 (52.2) 0.31   
HDL-C (mg/dL)
 Exercise 43.1 (6.6) 64.7 (7.8) < 0.001* 24.4 (17.9 to 27.9) < 0.001
 Usual Care 41.0 (4.3) 39.9 (4.0) 0.45   
Hemoglobin A1C (%)
 Exercise 7.5 (0.9) 2.9 (0.2) < 0.001* −4.6 (−11.2 to −1.6) < 0.001
 Usual Care 7.5 (0.8) 7.9 (0.8) 0.28   
Parent with MI before age 60 years, n (%)
 Exercise 40 (80) 40 (80)
 Usual Care 42 (84) 42 (84)    
10-year Risk RRS (%)
 Exercise 7.9 (0.9) 1.0 (0.5) < 0.001* −10.6 (−16.3 to −7.4) < 0.001
 Usual Care 9.0 (0.8) 11.6 (1.2) 0.002*   
  1. *P value for repeated-measures ANOVA comparing changes in the exercise group from baseline to post-intervention, and in the usual care group from baseline to post-intervention
  2. P value for mixed model analysis comparing changes between the exercise and usual care group from baseline to post-intervention
  3. Age and parent history of MI before 60 years calculated as unchanged during the 16-week intervention period