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Table 1 RT–HIIT resistance and high-intensity interval training, AT–HIIT moderate-intensity aerobic and high-intensity interval training, UC usual care, SD standard deviation, BMI body mass index, HER human epidermal growth factor receptor positivity, ER estrogen receptor positivity, MVPA objectively measured moderate- to vigorous-intensity physical activity, SED objectively measured sedentary behaviour. *One-way ANOVA, † Exact χ2 test, ** denotes p < 0.01

From: High intensity exercise during breast cancer chemotherapy - effects on long-term myocardial damage and physical capacity - data from the OptiTrain RCT

Participant characteristics at baseline

 

RT-HIIT

n = 29

AT-HIIT

n = 32

Usual care

n = 27

 
 

Mean ± SD

Mean ± SD

Mean ± SD

p-value*

Age

53.5 ± 10.2

53.7 ± 7.9

55.9 ± 7.5

0.52

Body mass (kg)

65.8 ± 9.4

67.0 ± 10.3

69.7 ± 12.5

0.40

Height (cm)

165.5 ± 6.1

166.6 ± 6.2

165.6 ± 6.3

0.75

BMI

24.0 ± 2.9

24.2 ± 3.3

25.4 ± 4.4

0.26

SED (min/day)

551.0 ± 102.3

534.2 ± 86.4

567.7 ± 68.03

0.34

MVPA (min/day)

97.7 ± 35.1

81.4 ± 24.7

70.0 ± 31.7

0.01**

 

%

%

%

p-value†

Married or partnered

69.0

62.5

63.0

0.78

University level education

69.0

68.8

59.3

0.55

Postmenopausal

51.7

59.4

74.0

0.22

Smoker

3.4

3.1

3.7

0.99

Radiotherapy

86.2

87.5

85.2

0.97

Anthracycline based chemotherapy

93.1

93.8

100

0.39

Tumor receptor status

   

0.76

 Triple negative

7

15.6

14.8

 

 HER2+, ER±

27.5

31.3

22.2

 

 HER2−, ER+

65.5

53.1

59.3

 

 HER2−, ER−

0

0

3.7

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