Fig. 2

Echocardiography of Treated vs Untreated Hearts. Mice in these studies were treated in study design I and study design II (see Table 1 in Methods section). LVIDd, left ventricular internal diameter end diastole; LVIDs, left ventricular internal diameter end systole; LVPWd, left ventricular posterior wall thickness, end diastole; LVPWs, left ventricular posterior wall thickness, end systole; IVSd, interventricular septal end diastole; IVSs, interventricular septal end systole; Heart Mass, direct measure; FS, fractional shortening; EF, ejection fraction; E/E’, ratio of mitral peak velocity of filling (E) to early diastolic mitral annular velocity (E’); Longitudinal Strain, long axis longitudinal strain (shortening); Radial Strain, long axis radial strain (thickening); Circumferential Strain, short axis circumferential strain (shortening); *p < 0.05