Fig. 2
From: CBR3 V244M is associated with LVEF reduction in breast cancer patients treated with doxorubicin
Comparison of ΔLVEF, SVI, EDVI and ESVI between CBR3 V244M genotypes. Baseline and 6-month echocardiographic images were used to calculate volumes and LVEF by blinded investigators. Volumetric indices were evaluated by normalizing cardiac volumes to body surface area (BSA). Baseline metrics were subtracted from 6-month values to calculate changes in a) LVEF, b) stroke volume index (SVI), c) end systolic volume index (ESVI) or d) end diastolic volume index (EDVI) between CBR3 V244M genotypes (AA, AG, GG) after DOX treatment. p = 0.040, one-way ANOVA. Data expressed as mean ± SEM