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Table 1 Levels of Evidence according to the Oxford Center of Evidence Based medicine (https://www.cebm.net/2009/06/oxford-centre-evidence-based-medicine-levels-evidence-march-2009/)

From: Evidence-based prediction and prevention of cardiovascular morbidity in adults treated for cancer

Level 1 a Systematic review of randomised controlled trials
  b Single randomised controlled trial
Level 2 a Systematic review of cohort studies
  b Individual cohort study
  c “Outcomes” research
Level 3 a Systematic review of Case-Control studies
  b Individual Case-Control study
Level 4   Case-series
Level 5   Expert opinion