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Table 1 Levels of Evidence according to the Oxford Center of Evidence Based medicine (https://www.cebm.net/2009/06/oxford-centre-evidence-based-medicine-levels-evidence-march-2009/)

From: Evidence-based prediction and prevention of cardiovascular morbidity in adults treated for cancer

Level

1

a

Systematic review of randomised controlled trials

 

b

Single randomised controlled trial

Level

2

a

Systematic review of cohort studies

 

b

Individual cohort study

 

c

“Outcomes” research

Level

3

a

Systematic review of Case-Control studies

 

b

Individual Case-Control study

Level

4

 

Case-series

Level

5

 

Expert opinion