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Fig. 2 | Cardio-Oncology

Fig. 2

From: A retrospective analysis of cardiovascular adverse events associated with immune checkpoint inhibitors

Fig. 2

Heart failure adverse events in cancer therapy. a Forest plot represents matched logistic regression model results for heart failure in cancer treatment groups (anti-PD-(L)1, anti-CTLA4, combination (more than one ICI), and chemotherapy). Shown are significant adjusted p-value (q < .05) odds ratio and their 95% confidence interval. Red boxes represent an odds ratio greater than one, favoring immunotherapy. Blue boxes indicate an odds ratio less than one, favoring chemotherapy. b Incidence of heart failure by cancer histology is shown. Each color represents which treatment group the case corresponded to. Red corresponds to anti-CTLA4, green to anti-PD-(L)1, blue to chemotherapy, and purple to combination immunotherapy. Anti-CTLA4 = anti-cytotoxic T-lymphocyte-associated protein 4; ICI = immune checkpoint inhibitor; anti-PD-(L)1 = anti-programmed death protein 1 and anti-programmed death-ligand 1

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