Fig. 7

Schema illustrating potential mechanisms in which chronic CVD and/or CVD-associated treatments may associate with cancer diagnosis (Cardio-Oncology Syndrome Type IV). Anticoagulation therapy may result in bleeding which unmasks cancer. Cardiovascular diagnostic radiation, including CT scans and cardiac catheterizations, may result in oxidative stress, DNA damage, and subsequent promotion of a cancer state. CT, Computerized Tomography; CV, cardiovascular