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Table 2 Propensity score adjusted multivariable regression of outcomes by aortic valve replacement versus medical management for cancer and non-cancer patientsa

From: TAVR and cancer: machine learning-augmented propensity score mortality and cost analysis in over 30 million patients

Variable OR (95%CI; p-value)
Mortality Cost (United States Dollars) Length of stay (Days)
Age by 10 years TAVR vs MM TAVR vs SAVR TAVR vs MM TAVR vs SAVR TAVR vs MM TAVR vs SAVR
Non-white race 1.01 (1.01–1.01) 1.00 (1.00–1.01) −43.90 (−47.04- -40.76) −3.66 (− 192.18–184.84) − 0.02 (− 0.02- -0.02) −0.06 (− 0.07- -0.05)
Zip code income 1.03 (1.02–1.04) 0.98 (0.78–1.23) 3953.27 (3833.21-4073.34) 31,486.94 (25,653.33-37,320.55) 0.31 (0.30–0.32) 1.12 (0.84–1.40)
1st quartile Reference Reference Reference Reference Reference Reference
2nd quartile 0.96 (0.95–0.98) 0.91 (0.71–1.16) 2120.83 (1976.57-2265.09) 4416.36 (− 1564.70-10,397.41) − 0.13 (− 0.15- -0.12) −0.20 (− 0.49–0.09)
3rd quartile 0.92 (0.90–0.93) 0.98 (0.77–1.25) 5372.67 (5224.71-5520.64) 16,506.95 (10,558.02-22,455.89) −0.17 (− 0.18- -0.16) −0.49 (− 0.78- -0.20)
4th quartile 0.93 (0.91–0.95) 0.92 (0.71–1.19) 9909.08 (9751.90-10,066.26) 31,220.53 (25,154.54-37,246.52) −0.11 (− 0.12- -0.09) −0.25 (− 0.54–0.04)
Procedure 0.52 (0.43–0.63) 0.90 (0.70–1.16) 164,413 (162,704.90-166,121.10) 52,098.41 (46,359.88-57,836.93) −0.01 (− 0.17–0.14) − 3.85 (− 4.13- -3.58)
Malignancy 1.08 (1.06–1.10) 1.07 (0.78–1.47) 2606.99 (2441.96-2772.02) − 7911.60 (− 15,835.76–12.55) 0.06 (0.05–0.08) − 0.89 (− 1.27- -0.51)
Metastases 1.95 (1.91–2.00) 0.63 (0.15–2.70) − 6706.27 (− 7033.93- -6378.60) 922.71 (− 575.25–22,025.82) − 0.31 (− 0.34- -0.28) 0.86 (− 0.81–2.54)
With Procedure 0.71 (0.45–1.11) 0.76 (0.43–1.32) −5186.04 (− 8627.01- -1745.08) 10,725.28 (− 575.25–22,025.82) − 0.72 (− 1.04- -0.40) 0.35 (− 0.20–0.89)
Mortality risk by DRG 7.88 (7.81–7.96) 10.74 (8.93–12.93) 8108.62 (8042.55-8174.68) 21,602.97 (18,898.19-24,307.74) 2.10 (2.09–2.10) 4.29 (4.18–4.41)
Length of stay, days    7514.37 (7505.36-7523.38) 14,544.34 (14,262.47-14,826.21)   
  1. aTAVR transcatheter aortic valve replacement, MM medical management, SAVR surgical aortic valve replacement, DRG Disease Related Group, bold = statistically significant