Table 3 Characteristics of patients who developed orthostatic hypotension or postural tachycardia syndrome after HCT
|  | Patients with OH (n = 30) | Patients with POTS (n = 12) | P-value |
|---|---|---|---|
Age, years | 57 [47–65] | 50 [39–58] | 0.1 |
Male sex | 20 (66.7) | 10 (83.3) | 0.45 |
Race | |||
 African-American | 8 (26.7) | 1 (8.3) | 0.43 |
 White | 20 (66.7) | 10 (83.3) | |
 Other | 2 (6.7) | 1 (8.3) | |
Hematologic diagnosis | |||
 Multiple myeloma | 6 (20.0) | 4 (33.3) | 0.67 |
 Myelodysplastic syndrome | 1 (3.3) | 1 (8.3) | |
 Myelofibrosis | 1 (3.3) | 1 (8.3) | |
 Acute myeloid leukemia | 5 (16.7) | 3 (25.0) | |
 Acute lymphatic leukemia | 4 (13.3) | 1 (8.3) | |
 Chronic myeloid leukemia | 1 (3.3) | 0 | |
 Chronic lymphatic leukemia | 0 | 0 | |
 Hodgkin’s lymphoma | 3 (10.0) | 0 | |
 Non-Hodgkin’s lymphoma | 6 (20.0) | 2 (16.7) | |
 Aplastic anemia | 0 | 0 | |
 Other | 3 (9.9) | 0 | |
Donor status | |||
 Related | 7 (23.3) | 2 (16.7) | 0.61 |
 Unrelated | 10 (33.3) | 6 (50.0) | |
BMT type | |||
 Autologous | 13 (43.3) | 4 (33.3) | 0.73 |
 Allogenic | 17 (56.7) | 8 (66.7) | |
CV diseases and risk factors | |||
 Hypertension | 12 (40.0) | 6 (50.0) | 0.73 |
 CAD | 1 (3.3) | 2 (16.7) | 0.19 |
 Heart failure | 5 (16.7) | 1 (8.3) | 0.66 |
 Diabetes mellitus | 1 (3.3) | 3 (25.0) | 0.06 |
 Hypercholesterolemia | 5 (16.7) | 5 (41.7) | 0.12 |
 Atrial fibrillation | 5 (16.7) | 3 (25.0) | 0.69 |
 Chronic kidney disease | 1 (3.3) | 1 (8.3) | 0.5 |
 Smoking | 0 | 1 (8.3) | 0.27 |
Pericarditis | 1 (3.3) | 1 (8.3) | 0.5 |
Previous treatment with anti-hypertensive drugs | |||
 b-blockers | 14 (46.7) | 8 (66.7) | 0.32 |
 Calcium-channel blockers | 5 (16.7) | 3 (25.0) | 0.67 |
 ACE inhibitors | 1 (3.3) | 1 (8.3) | 0.5 |
 ARBs | 1 (3.3) | 1 (8.3) | 0.5 |
 Furosemide/Torsemide | 2 (6.7) | 1 (8.3) | 1.00 |
 Spironolactone | 1 (3.3) | 2 (16.7) | 0.19 |
 None | 14 (46.7) | 2 (16.7) | 0.09 |
Number of anti-hypertensive drugs | |||
 1 | 9 (30.0) | 5 (41.7) | 0.1 |
 2 | 6 (20.0) | 4 (33.3) |  |
 3 | 1 (3.3) | 1 (8.3) |  |
 4 | 1 (3.3) | 0 |  |