Table 1 Key baseline cardiovascular data
From: Outcomes of malignancy in adults with congenital heart disease: a single center experience
Characteristic | Frequency (n = 68) |
|---|---|
Median age at most recent follow-up, yr (IQR) | 53.5 (40-66) |
Median age at first cancer diagnosis, yr (IQR) | 43.5 (31-60) |
Median follow-up since cancer diagnosis, yr (IQR) | 5 (3-11) |
Female sex (%) | 40 (59) |
ACHD Anatomic Complexity (%) | |
Class I | 12 (18) |
Class II | 32 (47) |
Class III | 24 (35) |
Single ventricle circulation (%) | 15 (22) |
Fontan palliation (%) | 12 (18) |
Systemic right ventricle in biventricular circulation (%) | 4 (6) |
Baseline cyanosis (%) | 6 (9) |
Prior cardiac surgery (%) | 53 (78) |
Arrhythmia prior to cancer diagnosis (%) | 30 (44) |
Supraventricular tachycardia | 19 (28) |
Atrial fibrillation | 12 (18) |
Ventricular arrhythmia | 1 (2) |
Sinus node dysfunction | 2 (3) |
Atrioventricular nodal block | 3 (4) |
Heart failure prior to cancer diagnosis (%) | 17 (25) |
NYHA Functional Class at baseline (%) | |
Class I | 53 (78) |
Class II | 13 (19) |
Class III | 2 (3) |
Medications prior to cancer diagnosis, n = 66 (%) | |
ACE-inhibitor/ angiotensin receptor blocker | 16 (24) |
Beta-blocker | 24 (36) |
Diuretic | 16 (24) |
Clinical Comorbidities | |
Diabetes Mellitus | 5 (7) |
Hypertension | 18 (27) |
Chronic kidney disease | 7 (10) |
Coronary artery disease (> 50% luminal stenosis) | 6 (9) |
Smoking History | 13 (19) |
Chronic liver disease | 16 (24) |