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Table 1 Baseline characteristics of patients included in the cardiac risk prediction model

From: Development of cardiac risk prediction model in patients with HER-2 positive breast cancer on trastuzumab therapy

Descriptive Statistics of the full data

Descriptive Statistics of Training Data Set in our Sensitivity Analysis

  

Incident cardiac dysfunction

 

Overall

No

Yes

P-value

n

415

376

39

 

Age.at.Dx (mean (SD))

58.40 (12.85)

58 43 (13.00)

58.13 (11.48)

0.891

Baseline.EF (mean (SD))

62.64 (5.75)

62.65 (5.83)

62.52 (4.92)

0.893

Stroke = 1 (%)

17 (4.1)

14 (3.8)

3 (7.9)

0.430

Diabetes = 1 (%)

61 (14.9)

50 (13.4)

11 (28.9)

0.020

Race.1 = white (%)

363 (87.9)

327 (87.4)

36 (92.3)

0.529

Radiation = 1 (%)

166 (40.0)

151 (40.2)

15 (38.5)

0.973

Adriamycin = 1 (%)

25 (6.1)

19 (5.1)

6 (15.4)

0.029

HTN = 1 (%)

200 (48.9)

178 (48.0)

22 (57.9)

0.320

CHF = 1 (%)

10 (2.4)

9 (2.4)

1 (2.6)

1.000

CAD = 1 (%)

33 (8.0)

28 (7.5)

5 (13.2)

0.367

Afib = 1 (%)

20 (4.9)

20 (5.4)

0 (0.0)

0.285

Renal.failure = 1 (%)

23 (5.6)

19 (5.1)

4 (10.5)

0.311

Tobacco.Hx (%)

   

0.837

Current smoker

58 (14.0)

53 (14.1)

5 (12.8)

 

Former smoker

101 (24.3)

90 (23.9)

11 (28.2)

 

Never smoked

256 (61.7)

233 (62.0)

23 (59.0)