Table 3 Adverse cardiac Events in Patients on TKIs with and without DM
Adverse Event | Myocardial Infarction, n (%) | Heart Failure, n (%) | Stroke, n (%) | Cardiac Mortality, n (%) | All-Cause Mortality, n (%) | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Yes | No | P Value | Yes | No | P Value | Yes | N o | P Value | Yes | No | P Value | Yes | No | P Value | |
Non-TKI (n = 265) | |||||||||||||||
Non DM (n = 213) | 65 (30.52) | 148 (69.48) | 0.9717 | 56 (26.29) | 157 (73.71) | 0.7092 | 14 (6.57) | 199 (93.43) | 0.7608 | 3 (1.41) | 210 (98.59) | 0.3894 | 79 (37.09) | 134 (62.91) | 0.7399 |
DM (n = 52) | 16 (30.77) | 36 (69.23) | 0.9717 | 15 (28.85) | 37 (71.15) | 0.7092 | 4 (7.69) | 48 (92.31) | 0.7608 | 0 (0.0) | 52 (100.0) | 0.3894 | 18 (34.62) | 34 (65.38) | 0.7399 |
TKIs (n = 186) | |||||||||||||||
Non DM (n = 148) | 35 (23.65) | 113 (76.35) | 0.7320 | 32 (21.62) | 116 (78.38) | 0.4264 | 5 (3.38) | 143 (96.62) | 0.0863 | 8 (5.41) | 140 (94.59) | 0.9723 | 61 (41.22) | 87 (58.78) | 0.9209 |
DM (n = 38) | 10 (26.32) | 28 (73.68) | 0.7320 | 6 (15.79) | 32 (84.21) | 0.4264 | 4 (10.53) | 34 (89.47) | 0.0863 | 2 (5.26) | 36 (94.74) | 0.9723 | 16 (42.11) | 22 (57.89) | 0.9209 |