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Table 4 Multiple linear regression modelsa showing effect of anthracycline dose on post-therapy ecg measures (N = 248)

From: Electrocardiograms for cardiomyopathy risk stratification in children with anthracycline exposure

Model

Outcome

Anthracycline dose estimate (mg/m2)

95% CI

P-value

1

ΣQRS (6 L)

– 0.001

– 0.002 to −0.0003

0.01

2

QTc

+  0.06

+  0.03 to + 0.09

< 0.001

  1. aAdjusted for sex, age at first dose, body surface area, race (white, black, Hispanic, other), time between pre- and post-therapy ECG measures, and pre-therapy ECG measures
  2. ΣQRS(6 L): sum of QRS amplitudes in 6 electrocardiogram limb leads, QTc: corrected QT interval
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Cardio-Oncology

ISSN: 2057-3804

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