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Table 3 Cancer diagnosis/type, chemotherapy agent class and radiation therapy (Medical Record Review cohort only)

From: Cardiotoxicity after cancer treatment: a process map of the patient treatment journey

N = 46

Mean (range)

n (%)

Cancer diagnosis

 Age at first cancer diagnosis (years)

53.6 (6.3–89.3)

46 (100)

  Bile duct

 

1 (2)

  Breast

 

14 (30)

  Colon

 

1 (2)

  Hodgkin’s lymphoma

 

1 (2)

  Leukaemia

 

3 (7)

  Lung

 

1 (2)

  Lymphoma

 

7 (15)

  Non-Hodgkin’s

 

11 (24)

  Oesophagus

 

1 (2)

  Osteosarcoma

 

4 (9)

  Prostate

 

1 (2)

  Missing

 

1 (2)

Agent Class

 Chemotherapy cyclesb,c

5.2 (1–18)

 

 Alkylating

Mean dose (mg)

 

  Carboplatin

520.0

2 (4)

  Chlorambucila

 

1 (2)

  Cisplatin

113.3

5 (11)

  Cyclophosphamide

1148.1

21 (48)

 Anthracyclines

  Doxorubicin

462.1

18 (39)

  Epirubicin

164.0

2 (4)

 Anthracycline combination

  ABVDa

 

1 (2)

 Antibiotic cytotoxics

  Bleomycin

20.0

1 (2)

 Antimetabolites

  ATRA Azacitidine therapy

100.0

1 (2)

  Adjuvant CTx with carboplatin/gemcitabinea

 

1 (2)

  Fluorouracil

980.0

3 (7)

  Methotrexate

63.0

5 (11)

  Fludarabine phosphatea

 

1 (2)

Mitotic Inhibitors

 Amsacrine

140.0

1 (2)

 Docetaxel

145.7

4 (9)

 Etoposide

200.0

1 (2)

 Paclitaxel

429.0

3 (7)

 Vincristinea

 

12 (26)

Monoclonal Antibodies

 Rituximab

655.0

11 (24)

 Trastuzumab

378.1

7 (15)

 Radiation therapy

 

28 (61)

  1. a Dose not recorded
  2. b Each patient’s regimen comprised individualised composites and doses of the above cytotoxic agents
  3. c Other drugs taken include: amiloride, amiodarone, amlodipine, atenolol, atorvastatin, bisoprolol, candesartan, carvedilol, cephalexin, cholecalciferol, clonidine, clopidogrel, digoxin, diltiazem, enalapril, enoxaparin, eprosartan, exemestane, frusemide, ibandronate, irbesartan, itraconazole, ivabradine, letrozole, lisinopril, metoprolol, telmisartan/hydrochlorothiazide, nebivolol, olmesartan, oxycodone, pantoprazole, perindopril, prazosin, prednisolone, ramipril, rivaroxaban, simvastatin, sotalol, spironolactone, tamoxifen, tazocin, goserelin zoledronic acid and vancomycin