Table 4 Multivariate analysis of hazard ratio of DFS with trastuzumab discontinuation
Variable | Adjusted Hazard Ratio | Std. Err. | 95% CI | P-value |
|---|---|---|---|---|
Discontinuation Trastuzumab | 4.38 | 1.95 | 1.83–10.46 | 0.001 |
Age | 0.99 | 0.02 | 0.97–1.03 | 0.750 |
Stage, 1 or 2 vs Stage 3 | 3.62 | 1.59 | 1.53–8.59 | 0.003 |
Grade, 1 or 2 vs Grade 3 | 1.39 | 0.56 | 0.63–3.06 | 0.416 |
ER status, Negative vs Positive | 0.60 | 0.26 | 0.25–1.42 | 0.242 |
Cardiomyopathy, Yes vs No | 0.25 | 0.14 | 0.08–0.75 | 0.014 |