Orthostatic intolerance syndromes after hematopoietic cell transplantation: clinical characteristics and therapeutic interventions in a single-center experience

Table 4 Logistic regression analysis showing the association between therapy and OH or POTS at univariate and multivariate analysis

	Univariate model			Multivariate model
	OR	95% CI	P-value	OR	95% CI	P-value
Radiotherapy	2.68	1.20–6.0	0.02	1.92	0.8–4.61	0.15
Anthracyclines	2.30	1.09–4.86	0.03	1.26	0.45–3.52	0.66
Corticosteroids	2.36	1.10–5.06	0.03	1.5	0.62–3.6	0.37
Anti-microtubules	2.89	1.32–6.34	0.01	1.15	0.32–4.12	0.83
Epipodophyllotoxin	2.85	1.3–6.25	0.01	1.90	0.71–5.1	0.20
Angiogenesis inhibitor	0.9	0.37–2.17	0.81
Histone-deacetylase inhibitors	0.42	0.05–3.67	0.43
Kinase inhibitors	1.09	0.40–2.93	0.87
Antimetabolites	0.95	0.44–2.07	0.9
Antitumor antibiotics	1.89	0.54–6.59	0.32
Proteasome inhibitors	0.87	0.38–1.99	0.75
Anti-thymocyte globulin	0.72	0.34–1.52	0.39
Alkylating agents	0.93	0.22–3.91	0.92

Statistically significant p values are displayed in bold characters
CI Confidence interval, OH Orthostatic hypotension, POTS Postural orthostatic tachycardia syndrome

ISSN: 2057-3804