Table 4 Cardiac treatments among 80 childhood and young adult cancer survivors with low left ventricular ejection fraction
Treatments | N (%) | LVEF 50–54.9% N = 38 (47.5%) | LVEF 41–49.9% N = 18 (25.0%) | LVEF < 41% N = 24 (30.0%) | P-valuea |
|---|---|---|---|---|---|
Medications | |||||
Any medication | 51 (63.8) | 16 (42.1) | 13 (72.2) | 22 (91.7) | < 0.001 |
ACEI/ARB | 37 (46.3) | 12 (31.2) | 8 (44.4) | 17 (70.8) | 0.010 |
Beta-blocker | 30 (37.5) | 7 (18.4) | 6 (33.3) | 17 (70.8) | < 0.001 |
Diuretics | 19 (23.8) | 5 (13.2) | 2 (11.1) | 12 (50.0) | 0.001 |
Aldosterone antagonists | 7 (8.8) | 1 (2.6) | 2 (11.1) | 4 (16.7) | 0.015 |
Statins | 28 (35.0) | 9 (23.7) | 8 (44.4) | 11 (45.8) | 0.130 |
Aspirin | 22 (27.5) | 6 (15.8) | 5 (27.8) | 11 (45.8) | 0.036 |
Surgical interventions | |||||
Any intervention | 12 (15.0) | 4 (10.5) | 2 (11.1) | 6 (24.0) | 0.260 |
Pacemaker/ICD | 11 (13.8) | 3 (7.9) | 1 (5.6) | 7 (29.2) | 0.031 |
Valve replacement | 7 (8.8) | 3 (7.9) | 2 (11.1) | 2 (8.3) | 0.921 |
Stent placement | 4 (5.0) | 2 (5.3) | 1 (5.6) | 1 (4.2) | 0.974 |
Coronary artery bypass | 4 (5.0) | 2 (5.3) | 0 (0.0) | 2 (8.3) | 0.469 |