Table 1 Characteristics
N = 804 | |
|---|---|
Sex | |
Male | 472 (59%) |
Female | 332 (41%) |
Age | |
Age 18–39 | 182 (23%) |
Age 40–59 | 406 (51%) |
Age >/= 60 | 216 (27%) |
Mean age | 49.7 years |
Mean body mass index | 28.8 kg/m2 |
Current smoker | 207 (26%) |
Race/Ethnicity | |
Non-Hispanic White | 749 (93%) |
Black | 38 (5%) |
Asian | 13 (2%) |
Other/unknown | 4 (1%) |
Primary Diagnosis | |
Acute myeloid leukemia | 401 (50%) |
Myelodysplastic syndrome | 132 (16%) |
Acute lymphoblastic leukemia | 91 (11%) |
Lymphoma | 72 (9%) |
Chronic lymphocytic leukemia | 37 (5%) |
Chronic myeloid leukemia | 37 (5%) |
Aplastic Anemia | 23 (3%) |
Myeloma | 7 (1%) |
Other | 4 (1%) |
Transplant Characteristics | |
Myeloablative conditioning regimen | 598 (74%) |
Total body irradiation | 278 (35%) |
Tyrosine Kinase inhibitor prior to transplant | 62 (8%) |
Donor Type | |
Matched unrelated | 442 (55%) |
HLA identical sibling | 275 (34%) |
Haploidentical | 75 (9%) |
Mismatched unrelated | 10 (1%) |
Pre-transplant Medical Comorbidity | |
Hypertension | 227 (28%) |
Diabetes | 80 (10%) |
Coronary artery disease | 46 (6%) |
Atrial arrhythmia | 41 (5%) |
PCI or CABG | 36 (5%) |
LVEF < 45% | 16 (3%) |
Congestive heart failure | 20 (3%) |
Valvular disease | 14 (2%) |
Cerebral vascular accident | 9 (1%) |