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Table 1 Baseline characteristics among CXRT and non-CXRT patients

From: Left atrial appendage volume as a prognostic Indicator of long-term mortality in Cancer survivors treated with thoracic radiation

Parameters

CXRT (n-43)

Non CXRT (n-141)

P value

Clinical variables

Age

80.9 ± 8.3

81.5 ± 9.2

0.72

BMI

26.9 ± 6.1

28.5 ± 6.2

0.14

Female, %

69.7

49.6

0.02*

White, %

95.4

93.6

0.39

STS score, mean

8.6 ± 4.5

8.3 ± 4.4

0.67

HTN, %

83.7

85.1

0.81

DM,%

34.8

29.7

0.57

HLD, %

69.7

56.0

0.12

Smoking, %

65.1

41.1

0.008*

CVA, %

55.8

4.3

< 0.0001*

COPD, %

34.9

43.3

0.38

CAD, %

62.8

51.1

0.22

ESRD, %

9.3

4.9

0.23

PAD, %

25.6

37.6

0.20

CABG, %

32.6

22.0

0.11

Cardiac surgery, %

32.7

26.2

0.44

3-coronary vessel disease, %

27.9

24.8

0.69

Ischemic cardiomyopathy (EF < 50%), %

14.0

19.1

0.50

Angina, %

34.9

28.4

0.45

Syncope, %

4.7

5.7

1.00

Lab variables

Creatinine in mg/dl, mean

1.3 ± 1.0

1.3 ± 1.0

0.98

FEV1, mean

79.6 ± 24.7

74.1 ± 24.4

0.19

eGFR, mean

52.9 ± 22.5

53.9 ± 21.1

0.78

Medications

Aspirin, %

81.6

61.7

0.02*

ACEI/ARB, %

21.1

35.5

0.11

Beta-blocker, %

75.6

78.7

0.67

Statins, %

69.8

56.0

0.11

Echo Variables

LVEF, mean

57.6 ± 11.7

55.2 ± 13.4

0.29

Mean AV gradient

45.4 ± 14.7

43.8 ± 15.3

0.54

Mod-severe MS, %

13.9

3.6

0.02 *

Mod-severe MR, %

23.3

14.2

0.16

Mod-severe AR, %

18.6

14.2

0.47

Mod-severe TR, %

16.3

11.3

0.43

  1. Values presented as n (%), mean (SD), or median (25-75th percentiles)
  2. (*) indicates p valve < 0.05 for patients in the CXRT group compared to non CXRT group. ACEI/ARB angiotensin converting enzyme inhibitor/angiotensin receptor blocker, AR aortic regurgitation, BMI body mass index, CAD coronary artery disease, CABG coronary artery bypass graft, COPD chronic obstructive pulmonary disease, CVA cerebrovascular accident, DM diabetes mellitus, ESRD end stage renal disease, eGFR estimated glomerular filtration rate, FEV1 force expiratory volume at 1 second, HTN hypertension, HLD hyperlipidemia, PAD peripheral arterial disease, LVEF left ventricular ejection fraction, MS mitral stenosis, MR mitral regurgitation, STS surgical thoracic society, TR tricuspid regurgitation