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Table 4 Fit Proportional Hazard Analysis for all-cause mortality

From: Left atrial appendage volume as a prognostic Indicator of long-term mortality in Cancer survivors treated with thoracic radiation

Univariate

Multivariate

Parameters

RR

95% CI

P value

RR

95% CI

P value

Clinical variables

Age

0.97

0.93–1.02

0.35

   

BMI

0.97

0.90–1.04

0.43

   

White

0.70

0.09–5.27

0.73

   

STS score, mean

1.03

0.94–1.11

0.43

   

HTN, %

2.83

0.37–21.14

0.23

   

DM,%

0.76

0.31–1.86

0.55

   

HLD, %

1.14

0.50–2.62

0.74

   

Smoking, %

1.72

0.74–3.97

0.19

   

CVA, %

2.83

1.23–6.49

0.02*

1.85

0.90–3.82

0.09

COPD, %

1.35

0.60–3.03

0.47

   

CAD, %

1.67

0.68–4.04

0.25

   

ESRD, %

1.93

0.44–8.35

0.41

   

PAD, %

1.69

0.74–3.86

0.21

   

CABG, %

1.09

0.43–2.79

0.86

   

Cardiac surgery, %

0.97

0.34–2.49

0.95

   

3 Vessel Disease, %

0.96

0.38–2.44

0.94

   

ICM (EF < 50%), %

2.23

0.89–5.54

0.10

   

Angina, %

0.88

0.36–2.14

0.78

   

Syncope, %

2.28

0.65–7.95

0.24

   

Lab Variables

Creatinine in mg/dl, mean

1.2

0.91–1.54

0.14

   

FEV1, mean

0.98

0.96–1.01

0.07

   

eGFR, mean

0.99

0.97–1.01

0.66

   

Echo and CCT variables

Mod -severe MS, %

2.74

0.91–8.24

0.11

   

Mod-severe AR, %

1.02

0.36–2.85

0.97

   

Mod-severe MR, %

1.16

0.43–3.14

0.76

   

Mod-severe TR, %

1.60

0.60–4.27

0.36

   

LAV, ml

1.00

0.99–1.02

0.13

   

LAVI, ml/m2

1.00

0.99–1.02

0.36

   

#LAAV, ml

1.05

1.01–1.08

0.009*

1.03

1.0–1.01

0.01*

#LAAVI, ml/m2

1.07

1.0–1.13

0.03*

1.05

1.0–1.01

0.03*

RSPV ostium, cm2

0.85

0.57–1.21

0.39

   

RIPV ostium, cm2

1.31

0.93–1.78

0.12

   

LSPV ostium, cm2

0.72

0.45–1.08

0.12

   

LIPV ostium, cm2

1.12

0.79–1.41

0.45

   

LVEF

0.98

0.95–1.02

0.42

   

Mean AV gradient, mmHg

1.01

0.98–1.04

0.49

   

Medications

Aspirin, %

1.20

0.49–2.91

0.67

   

ACEI/ARBs, %

0.78

0.31–1.98

0.61

   

Beta blocker, %

0.82

0.30–2.21

0.69

   

Statins, %

1.14

0.50–2.62

0.74

   
  1. #, Only one variable modeled during multivariate analysis as both represented the similar data
  2. Values presented as n (%), mean (SD), or median (25-75th percentiles)
  3. (*) indicates p valve < 0.05 for patients in the CXRT group compared to non CXRT group. ACEI/ARB angiotensin converting enzyme inhibitor/angiotensin receptor blocker, AR aortic regurgitation, BMI body mass index, CAD coronary artery disease, CABG coronary artery bypass graft, COPD chronic obstructive pulmonary disease, CVA cerebrovascular accident, DM diabetes mellitus, ESRD end stage renal disease, eGFR estimated glomerular filtration rate, FEV1 force expiratory volume at 1 second, HTN hypertension, HLD hyperlipidemia, ICM ischemic cardiomyopathy, LAV left atrial volume, LAVI left atrial volume index, LAAV left atrial appendage volume, LAAVI left atrial appendage volume index, PAD peripheral arterial disease, LVEF left ventricular ejection fraction, MS mitral stenosis, MR mitral regurgitation, STS surgical thoracic society, TR tricuspid regurgitation