Table 1 Baseline characteristics of the study population

2737

297

5390

578

Age(year)

70.00(60.00,80.00)

73.00(65.00,80.00)

0.004

65.00 (56.00, 76.00)

75.00 (66.00, 82.75)

 < 0.001

Gender(%)

0.978

0.007

 Male

1716(62.7)

187(63.0)

3418 (63.4)

333 (57.6)

 Female

1021(37.3)

110(37.0)

1972 (36.6)

245 (42.4)

Weight(kg)

80.00(68.00,94.43)

72.00(62.50,87.60)

 < 0.001

83.00 (70.00, 98.30)

76.94 (64.46, 90.07)

 < 0.001

Severe score

 APS

43.00(30.00,62.00)

52.00(40.00,70.00)

 < 0.001

32.00 (23.00, 47.00)

38.00 (27.00, 52.50)

 < 0.001

First care unit(%)

 < 0.001

0.097

 NonCCU

751(27.4)

171(57.6)

2849 (52.9)

327 (56.6)

 CCU

1986(72.6)

126(42.4)

2541 (47.1)

251 (43.4)

PCI(%)

0.003

0.001

 no

1619(59.2)

203(68.4)

4002 (74.2)

466 (80.6)

 yes

1118(40.8)

94(31.6)

1388 (25.8)

112 (19.4)

CABG(%)

 < 0.001

0.961

 no

2307(84.3)

285(96.0)

5220 (96.8)

559 (96.7)

 yes

430(15.7)

12(4.0)

170 ( 3.2)

19 ( 3.3)

Ventilator(%)

0.549

0.124

 no

1521(55.6)

171(57.6)

2461 (45.7)

244 (42.2)

 yes

1216(44.4)

126(42.4)

2929 (54.3)

334 (57.8)

Vasopressor(%)

0.370

0.001

 no

1872(68.4)

195(65.7)

4829 (89.6)

490 (84.8)

 yes

865(31.6)

102(34.3)

561 (10.4)

88 (15.2)

Dialysis (%)

0.271

0.512

 no

2685(98.1)

288(97.0)

5252 (97.4)

560 (96.9)

 yes

52(1.9)

9(3.0)

138 ( 2.6)

18 ( 3.1)

Comorbidities(%)

congestive heart failure

0.005

 no

1255(45.9)

157(52.9)

4664 (86.5)

475 (82.2)

 yes

1482(54.1)

140(47.1)

726 (13.5)

103 (17.8)

hypertension

0.105

 < 0.001

 no

1622(59.3)

191(64.3)

2331 (43.2)

204 (35.3)

 yes

1115(40.7)

106(35.7)

3059 (56.8)

374 (64.7)

cerebrovascular disease

0.053

0.004

 no

2366(86.4)

244(82.2)

4997 (92.7)

516 (89.3)

 yes

371(13.6)

53(17.8)

393 ( 7.3)

62 (10.7)

chronic pulmonary disease

0.016

 < 0.001

 no

2119(77.4)

211(71.0)

4791 (88.9)

472 (81.7)

 yes

618(22.6)

86(29.0)

599 (11.1)

106 (18.3)

renal failure

0.813

0.006

 no

1885(68.9)

202(68.0)

4190(95.9)

444(93.1)

 yes

852(31.1)

95(32.0)

178(4.1)

33(6.9)

liver disease

0.230

0.021

 no

2537(92.7)

269(90.6)

5351 (99.3)

568 (98.3)

 yes

200(7.3)

28(9.4)

39 ( 0.7)

10 ( 1.7)

diabetes

1.000

0.171

 no

1628(59.5)

177(59.6)

3687 (68.4)

412 (71.3)

 yes

1109(40.5)

120(40.4)

1703 (31.6)

166 (28.7)

Vital signs

 BP

59.00(51.00,66.00)

56.00(50.00,64.00)

0.003

119.00 (105.00, 136.00)

116.00 (102.00, 132.00)

0.002

 Heart rate

66.00(59.00,76.00)

70.00(62.00,82.00)

 < 0.001

78.00 (67.00, 90.00)

80.00 (68.00, 92.00)

0.110

 Respiratory rate

12.00(10.00,14.50)

13.00(10.00,16.00)

 < 0.001

18.00 (16.00, 22.00)

18.00 (16.00, 22.00)

0.449

 Temperature

36.44(36.22,36.67)

36.44(36.33,36.67)

0.544

36.72 (36.50, 36.94)

36.61 (36.39, 36.89)

 < 0.001

Laboratory tests

 Max troponin T/I

1.37 (0.36, 4.13)

0.79 (0.23, 1.93)

 < 0.001

8.73 (1.69, 32.78)

5.72 (1.19, 17.96)

 < 0.001

 WBC(K/uL)

10.80(8.10,14.40)

9.70(7.40,14.40)

0.044

10.70 (8.30, 14.00)

10.30 (7.40, 14.20)

0.032

 hemoglobin(g/dl)

11.60(9.80,13.40)

9.80(8.20,11.20)

 < 0.001

13.40 (11.60, 14.90)

11.90 (10.10, 13.60)

 < 0.001

 platelet(K/uL)

208.00(162.00,262.00)

184.00(127.50,267.00)

0.001

222.00 (179.00, 274.00)

210.00 (162.00, 272.00)

0.001

 potassium(mEq/L)

4.20(3.90,4.60)

4.30(3.90,4.70)

0.072

4.00 (3.70, 4.40)

4.10 (3.80, 4.50)

0.015

 calcium(mEq/L)

8.60(8.20,9.00)

8.50(8.00,9.00)

0.006

8.90 (8.40, 9.30)

8.80 (8.30, 9.30)

0.015

 sodium(mEq/L)

138.00(136.00,141.00)

137.00(134.00,140.00)

 < 0.001

138.00 (135.00, 140.00)

138.00 (135.00, 140.00)

0.172

 bicarbonate(mEq/L)

23.00(20.00,25.00)

22.00(18.00,25.00)

0.005

24.00 (22.00, 27.00)

24.00 (22.00, 27.00)

0.877

 creatinine(mg/dl)

1.10(0.80,1.80)

1.20(0.90,1.70)

0.264

1.06 (0.85, 1.43)

1.15 (0.90, 1.59)

 < 0.001

 glucose(mg/dl)

139.00(111.00,193.00)

127.00(104.00,166.00)

 < 0.001

138.00 (112.00, 193.00)

137.00 (115.00, 188.00)

0.975

Outcome

 All-cause in-hospital mortality (%)

 < 0.001

 < 0.001

 no

2281(83.3)

196(66.0)

4938(91.6)

494(85.5)

 yes

456(16.7)

101(34.0)

452( 8.4)

84(14.5)

 Length of hospital stay (day)

6.98(3.65, 12.08)

8.82(3.88, 14.97)

 < 0.001

3.43(2.15, 6.77)

4.37(2.52, 8.15)

 < 0.001