Table 1 Patient Characteristics and Cardiac Risk Factors
From: Effect of insulin resistance on CAC scores in cancer survivors
Insulin Sensitive (N = 32) | IR - Prediabetic (N = 29) | IR - Diabetic (N = 29) | Total (N = 90) | P-value | |
|---|---|---|---|---|---|
Age | 0.071 | ||||
Mean (SD) | 60.9 (10.5) | 66.1 (9.8) | 65.5 (8.2) | 64.1 (9.7) | |
Range | 45.0–87.0 | 43.0–82.0 | 49.0–82.0 | 43.0–87.0 | |
Gender - Male | 11 (34.4%) | 15 (51.7%) | 12 (41.4%) | 38 (42.2%) | 0.395 |
Race | < 0.001 | ||||
African/AA | 8 (25.0%) | 4 (13.8%) | 13 (44.8%) | 25 (27.8%) | |
Asian | 1 (3.1%) | 1 (3.4%) | 1 (3.4%) | 3 (3.3%) | |
Caucasian | 23 (71.9%) | 18 (62.1%) | 8 (27.6%) | 49 (54.4%) | |
Hispanic | 0 (0.0%) | 6 (20.7%) | 7 (24.1%) | 13 (14.4%) | |
Height (m) | 0.284 | ||||
Mean (SD) | 1.7 (0.1) | 1.6 (0.1) | 1.6 (0.1) | 1.7 (0.1) | |
Range | 1.5–1.9 | 1.5–1.8 | 1.4–1.9 | 1.4–1.9 | |
Weight (kg) | 0.006 | ||||
Mean (SD) | 74.2 (13.1) | 77.1 (16.4) | 88.1 (21.6) | 79.6 (18.1) | |
Range | 52.0–103.4 | 50.3–131.0 | 59.4–136.8 | 50.3–136.8 | |
BMI | < 0.001 | ||||
Mean (SD) | 26.5 (5.2) | 28.4 (5.7) | 32.8 (7.7) | 29.1 (6.7) | |
Range | 19.6–39.7 | 18.9–48.1 | 22.1–50.6 | 18.9–50.6 | |
BMI (categorical) | 0.029 | ||||
Normal | 14 (43.8%) | 7 (24.1%) | 4 (13.8%) | 25 (27.8%) | |
Overweight | 12 (37.5%) | 11 (37.9%) | 9 (31.0%) | 32 (35.6%) | |
Obese | 6 (18.8%) | 11 (37.9%) | 16 (55.2%) | 33 (36.7%) | |
Smoking Status | 0.809 | ||||
Missing | 1 | 3 | 0 | 4 | |
Current | 5 (16.1%) | 4 (15.4%) | 2 (6.9%) | 11 (12.8%) | |
Former | 9 (29.0%) | 9 (34.6%) | 11 (37.9%) | 29 (33.7%) | |
Never | 17 (54.8%) | 13 (50.0%) | 16 (55.2%) | 46 (53.5%) | |
Pack Years | 0.362 | ||||
Mean (SD) | 23.4 (17.1) | 42.0 (56.5) | 22.0 (36.0) | 29.0 (39.5) | |
Range | 0.5–70.0 | 0.4–200.0 | 1.0–130.0 | 0.4–200.0 | |
Hyperlipidemia | 22 (68.8%) | 21 (72.4%) | 22 (75.9%) | 65 (72.2%) | 0.802 |
Family Hx Heart Attack | 10 (31.2%) | 4 (13.8%) | 10 (34.5%) | 24 (26.7%) | 0.170 |
Total Cholesterol | 0.117 | ||||
Mean (SD) | 196.3 (42.8) | 186.0 (45.5) | 172.4 (45.4) | 185.3 (45.1) | |
Range | 99.0–299.0 | 91.0–281.0 | 88.0–277.0 | 88.0–299.0 | |
HDL | < 0.001 | ||||
Mean (SD) | 69.5 (19.6) | 54.6 (13.3) | 51.1 (13.9) | 58.8 (17.8) | |
Range | 42.0–115.0 | 27.0–76.0 | 31.0–81.0 | 27.0–115.0 | |
Systolic BP | 0.687 | ||||
Mean (SD) | 126.8 (15.5) | 130.1 (16.4) | 129.9 (18.9) | 128.9 (16.8) | |
Range | 94.0–164.0 | 96.0–162.0 | 98.0–160.0 | 94.0–164.0 | |
Diastolic BP | 0.256 | ||||
Mean (SD) | 75.8 (11.3) | 72.1 (12.5) | 71.2 (10.1) | 73.1 (11.4) | |
Range | 52.0–100.0 | 44.0–98.0 | 50.0–93.0 | 44.0–100.0 | |
On Lipid Lowering Drugs | 5 (15.6%) | 7 (24.1%) | 19 (65.5%) | 31 (34.4%) | < 0.001 |
Framingham CV Risk (Men) | 0.038 | ||||
Mean (SD) | 16.9 (8.5) | 20.8 (10.0) | 30.0 (15.9) | 23.3 (13.3) | |
Range | 4.4–27.8 | 10.5–46.9 | 10.6–61.0 | 4.4–61.0 | |
Framingham CV Risk (Women) | < 0.001 | ||||
Mean (SD) | 7.1 (4.1) | 9.1 (3.9) | 17.5 (11.4) | 10.6 (8.0) | |
Range | 2.5–17.9 | 2.3–16.7 | 4.5–47.2 | 2.3–47.2 | |
ACC/AHA (ASCVD) | < 0.001 | ||||
Mean (SD) | 8.5 (8.3) | 14.1 (10.0) | 23.0 (13.7) | 15.0 (12.3) | |
Range | 0.8–36.3 | 1.2–35.1 | 3.8–61.6 | 0.8–61.6 |