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Table 2 Echocardiographic parameters in the cardiotoxic group

From: Detection of right ventricular dysfunction by three – dimensional echocardiography and two - dimensional speckle tracking in breast cancer patients receiving anthracycline- based chemotherapy

Variables

Baseline

End

6 m.

9 m.

P1

P2

LVEF

62.44 ± 4.50

60.78 ± 4.51

58.89 ± 4.76

47.89 ± 3.88

0.085

0.001*

LVGLS

-21.21 ± 1.59

-20.37 ± 1.53

-17.49 ± 1.07

-15.22 ± 1.18

0.001*

0.001*

SPAP

14.11 ± 3.82

14.28 ± 3.37

16.44 ± 4.46

17.56 ± 5.36

0.374

0.088

RV-S

14.56 ± 1.79

13.78 ± 1.59

13.24 ± 1.73

13.04 ± 2.36

0.170

0.081

TAPSE

1.95 ± 0.19

1.94 ± 0.18

1.90 ± 0.11

1.82 ± 0.13

0.776

0.069

FAC

44.83 ± 4.44

44.50 ± 3.94

41.44 ± 4.23

38.00 ± 3.76

0.072

0.001*

RV EDV

86.78 ± 9.16

87.50 ± 8.97

95.78 ± 9.23

105.00 ± 8.98

0.021*

0.001*

RV ESV

42.50 ± 5.98

42.89 ± 5.92

50.44 ± 7.01

61.28 ± 8.45

0.005*

0.001*

RV EF

51.13 ± 3.09

51.12 ± 2.83

48.47 ± 3.59

43.82 ± 4.68

0.130

0.001*

RV FWLS

-24.67 ± 1.27

-24.62 ± 1.26

-22.22 ± 1.41

-19.23 ± 1.54

0.001*

0.001*

RV GLS

-22.54 ± 0.79

-22.44 ± 0.76

-19.53 ± 1.32

-17.86 ± 1.33

0.001*

0.001*

  1. P1: Baseline values compared with 6 months
  2. P2: Baseline values compared with 9 months
  3. *: means significant
  4. LVEF: left ventricle ejection fraction, LVGLS: left ventricle global longitudinal strain, SPAP: systolic pulmonary artery pressure, RV-S: right ventricle systolic wave, TAPSE: Tricuspid annular plane systolic excursion, FAC: fractional area change, RV EDV: right ventricle end-diastolic volume, RV ESV: right ventricle end-systolic volume, RV EF: right ventricle ejection fraction, RVFWLS: right ventricular free wall longitudinal strain, and RVGLS: right ventricular global longitudinal strain