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Table 4 Univariate and multivariate analysis between the cumulative dose of anthracycline and the echocardiographic parameters in the cardiotoxic group

From: Detection of right ventricular dysfunction by three – dimensional echocardiography and two - dimensional speckle tracking in breast cancer patients receiving anthracycline- based chemotherapy

Variables

Univariate

Multivariate

OR (95% CI)

P value

OR (95% CI)

P value

∆ RVFWLS

0.484 (0.283–0.619)

0.001*

0.519 (0.319–0.759)

0.001*

∆ LVGLS

0.627 (0.218–0.894)

0.001*

0.725 (0.367–0.926)

0.009*

∆ RVEDV

1.512 (1.386–2.829)

0.036*

1.625 (0.237–1.805)

0.095

∆ RVESV

2.695 (1.365–4.841)

0.013*

1.828 (0.199–3.748)

0.081

∆ RVGLS

0.482 (0.296–0.748)

0.028*

0.734 (0.329–2.652)

0.102

  1. ∆ : changes in the measurements between baseline and 6 months after the end of therapy
  2. LVGLS: left ventricle global longitudinal strain, RV EDV: right ventricle end-diastolic volume, RV ESV: right ventricle end-systolic volume, RVFWLS: right ventricular free wall longitudinal strain, and RVGLS: right ventricular global longitudinal strain