Fig. 1

Diagnostic Workflow for CAR-T Patients

The standard clinical practice at our institution includes comprehensive cardiac evaluation including transthoracic echocardiogram, electrocardiogram and cardiac biomarkers. During the index hospitalization after CAR-T infusion, close surveillance for adverse cardiac events occurs with follow-up cardiac biomarkers. If a patient develops cytokine release syndrome grade 2 or higher or develop new onset cardiotoxicity, an electrocardiogram and cardiac biomarkers are obtained.