Table 3 Post-CAR-T Clinical Manifestation Based on Cardiac Events
Variables | Cardiac Events (N = 11) | No Cardiac Events (N = 79) | P Value |
|---|---|---|---|
Maximum CRS Grade | |||
 0 | 0 (0.0%) | 14 (17.7%) |  |
 1 | 5 (45.5%) | 40 (50.6%) |  |
 2 | 5 (45.5%) | 24 (30.4%) |  |
 3 | 1 (9.1%) | 0 (0.0%) |  |
 4 | 0 (0.0%) | 0 (0.0%) |  |
 5 | 0 (0.0%) | 1 (1.3%) |  |
CRS Classification | Â | 0.247 | |
 Grade 0/1 CRS | 5 (45.5%) | 54 (68.4%) |  |
 Grade 2 or above CRS | 6 (54.5%) | 25 (31.6%) |  |
Tocilizumab Administration | Â | 0.368 | |
 Yes | 8 (72.7%) | 42 (53.2%) |  |
 No | 3 (27.3%) | 37 (46.8%) |  |
Peak CRP (mg/dL) | 11.7 [ 8.5;15.7] | 13.0 [ 6.2;17.2] | 1 |
Troponin Level, Day 5 (ng/mL) | 0.010 [0.010;0.010] | 0.010 [0.010;0.017] | 0.307 |
BNP Level, Day 5 (pg/mL) | 125.0 [86.0;268.0] | 63.0 [21.0;124.0] | 0.019 |