Simultaneous exercise stress cardiac magnetic resonance and cardiopulmonary exercise testing to elucidate the Fick components of aerobic exercise capacity: a feasibility and reproducibility study and pilot study in hematologic cancer survivors

Table 2 Comparison of Test-Retest ExeCMR + CPET Peak Exercise Values in Reproducibility Healthy Cohort

Fick Variables	Test	Retest	_meandiff	SD_diff	SEM	SDC_ind	SDC_group	95%LOA
BSA VO₂,
L·min^− 1/m²	0.984 ± 0.235	0.981 ± 0.240	0.003	0.045	0.032	0.088	0.033	-0.085, 0.091
Relative VO₂,
mL·kg^− 1·min^− 1	24.9 ± 4.8	24.8 ± 5.08	0.114	1.162	0.822	2.3	0.9	-2.2, 2.3
Cardiac Index,
L·min^− 1/m²	7.96 ± 0.966	8.04 ± 0.888	0.082	0.318	0.225	0.62	0.24	-0.71, 0.54
SVI, mL/m²/beat	59.8 ± 7.1	60.4 ± 8.0	0.533	2.163	1.530	4.2	1.6	-4.8, 3.7
a-vO₂ difference,
mLO₂/dL	12.28 ± 2.06	12.08 ± 1.99	0.200	0.892	0.631	1.75	0.66	-1.55, 1.95
Other CPET Variables
VE/VCO₂ slope	27.4 ± 2.6	28.2 ± 2.1	0.74	2.077	1.468	4.07	1.54	-3.33, 4.07
OUES	1.91 ± 0.6	1.91 ± 0.6	0.003	0.144	0.102	0.28	0.11	-0.28, 0.28
Rest PetCO₂	38.0 ± 4.9	37.5 ± 4.1	0.49	2.889	2.042	5.7	2.14	-5.18, 6.15
PetCO₂ at VAT	43.0 ± 3.4	42.3 ± 3.0	0.71	3.904	2.760	7.6	2.89	-6.94, 8.37

Data are expressed as mean ± SD.
Abbreviations: a-vO₂ = arteriovenous oxygen; BSA = body surface area; ExeCMR + CPET = exercise cardiac magnetic resonance + cardiopulmonary exercise test; LOA = limits of agreement; _meandiff=mean test-retest difference; OUES = oxygen uptake efficiency slope; PetCO₂ = partial pressure end-tidal carbon dioxide; SD_diff=standard deviation of the difference; SDC_group= smallest detectable change of group; SDC_ind=smallest detectable change of individual; SEM = standard error of measurement; SVI = stroke volume index; VAT = ventilatory anaerobic threshold; VE/VCO₂ = minute ventilation to carbon dioxide production; VO₂ = oxygen consumption.

ISSN: 2057-3804