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Table 3 Association between diagnostic tests and survival time and 180 day mortality risk among people with ICI myocarditis who develop CHB

From: Complete heart block is a significant predictor of mortality in immune checkpoint inhibitor myocarditis

Diagnostic test

Association with survival

P-value for mortality risk*

N = 

Spearman’s rho

p-value

(ranksum)

 

Laboratory tests

 White blood cell count

-0.775

0.041

0.245

7

 Troponin T

-0.943

0.0048

0.143

6

 NT pro-BNP

0.3

0.624

0.157

3

 Creatine Kinase

0

1.000

0.480

5

 AST

-0.306

0.504

0.699

5

 ALT

-0.487

0.268

0.699

7

 Albumin

-0.638

0.173

0.766

6

ECG at admission

 Ventricular rate

0.812

0.0499

0.245

6

 PR interval

0.290

0.637

0.643

5

 QRS duration

-0.633

0.128

0.121

7

 QT interval

0.479

0.277

0.241

7

 QTc interval

-0.316

0.490

0.439

7

 Sokolow Lyon Index

-0.655

0.158

0.143

6

Treatment

Exact p-value

 

 IVIG

  

0.858 *

7

 Temporary pacemaker

  

0.130 *

7

 Permanent pacemaker

  

0.051*

7

  1. *Fisher’s exact test