Table 4 Association between clinical risk factors and complete heart block among patients with ICI myocarditis using unadjusted logistic regression
N = | OR (95% CI) | p-value** | |
|---|---|---|---|
Laboratory results | |||
Troponin T | 33 | 1.00 (1.00 to 1.00) | 0.555 |
Creatine kinase | 24 | 1.00 (1.00 to 1.00) | 0.165 |
WBC count | 34 | 1.143 (0.93 to 1.40) | 0.203 |
AST | 30 | 1.006 (1.0 to 1.01) | 0.058 |
ALT | 30 | 1.005 (0.998 to 1.01) | 0.190 |
NT pro-BNP | 17 | 0.998 (0.99 to 1.00) | 0.362 |
ECG findings | |||
Ventricular rate | 34 | 0.964 (0.92 to 1.01) | 0.107 |
First degree AV block * (PR interval > 200 ms) | 28 | 10.0 (1.15 to 86.88) | 0.037 |
QRS duration * ≥ 130 ms | 24 | 26.4 (2.57 to 271.09) | 0.006 |
QT interval | 34 | 1.009 (0.997 to 1.02) | 0.152 |
QTc interval | 34 | 0.997 (0.98 to 1.02) | 0.791 |
Sokolow Lyon index | 33 | 0.758 (0.60 to 0.96) | 0.023 |
Dual ICI treatment | 34 | 3.3 (0.554 to 19.65) | 0.190 |
Ejection fraction on TTE | 29 | 1.109 (0.995 to 1.24) | 0.060 |