Table 1 Characteristics for all included patients
CVD (-) | Cardioonc (-) | Cardioonc ( +) | CVD ( +) | Total | p-value* | |
|---|---|---|---|---|---|---|
n(%) | n(%) | n(%) | n(%) | N(%) | ||
Patients | 309,086(74) | 65,821(15.7) | 1414(0.3) | 41,985(10.0) | 418,306 (100) | |
Age < = 65 | 134,225(46.7) | 21,471(34.3) | 495(36.7) | 14,202(37.1) | 170,393(43.7) | < 0.001 |
Age > 65 | 153,357(53.3) | 41,210(65.7) | 852(63.3) | 24,029(62.9) | 219,448(56.3) | |
Females | 135,466(43.8) | 33,503(50.9) | 697(49.3) | 18,171(43.3) | 187,837(44.9) | < 0.001 |
White Race | 213,590(69.9) | 50,946(77.8) | 1020(72.7) | 26,689(64.8) | 292,245(70.7) | |
Comorbidities | ||||||
Alcohol Abuse | 31,569(10.2) | 5866(8.9) | 103(7.3) | 2815(6.7) | 40,353(9.6) | < 0.001 |
Asthma | 11,059(3.6) | 2616(4) | 81(5.7) | 1636(3.9) | 15,392(3.7) | < 0.001 |
Atrial fibrillation/Flutter | 100,962(32.7) | 21,392(32.5) | 488(34.5) | 14,086(33.6) | 136,928(32.7) | < 0.001 |
Cerebrovascular Diseases | 60,334(19.5) | 12,024(18.3) | 245(17.3) | 6852(16.3) | 79,455(19.0) | < 0.001 |
Chronic Heart Failure | 135,556(43.9) | 25,021(38) | 623(44.1) | 19,785(47.1) | 180,985(43.3) | < 0.001 |
Chronic Ischemic Heart Disease | 205,566(66.5) | 42,410(64.4) | 853(60.3) | 28,195(67.2) | 277,024(66.2) | < 0.001 |
Chronic Kidney Disease | 103,117(33.4) | 24,505(37.2) | 650(46) | 17,063(40.6) | 145,335(34.7) | < 0.001 |
COPD | 24,923(8.1) | 8983(13.6) | 204(14.4) | 3506(8.4) | 37,616(9.0) | < 0.001 |
Diabetes | 129,406(41.9) | 25,523(38.8) | 649(45.9) | 22,283(53.1) | 177,861(42.5) | < 0.001 |
Dyslipidemia | 210,353(68.1) | 46,153(70.1) | 998(70.6) | 28,779(68.5) | 286,283(68.4) | < 0.001 |
History CABG | 13,188(4.3) | 2286(3.5) | 40(2.8) | 1319(3.1) | 16,833(4.0) | < 0.001 |
Hypertension | 234,950(76.0) | 53,180(80.8) | 1190(84.2) | 31,978(76.2) | 321,298(76.8) | < 0.001 |
Pacemaker ICD | 2827(0.9) | 733(1.1) | 24(1.7) | 409(1) | 3993(1) | < 0.001 |
Peripheral Vascular Disease | 214,861(69.5) | 45,745(69.5) | 945(66.8) | 29,209(69.6) | 290,760(69.5) | < 0.001 |
Prior Heart Transplant | 3032(1) | 867(1.3) | 24(1.7) | 350(0.8) | 4273(1) | < 0.001 |
Prior Heart Valve | 25,645(8.3) | 3730(5.7) | 62(4.4) | 1940(4.6) | 31,377(7.5) | < 0.001 |
Valvular Heart Disease | 162,957(52.7) | 38,163(58) | 797(56.4) | 16,802(40) | 218,719(52.3) | < 0.001 |
Antineoplastic agents | ||||||
Cytotoxic agents | 0(0) | 19,654(29.9) | 791(55.9) | 0(0) | 20,445(4.9) | < 0.001 |
Immunotherapy | 0(0) | 6525(9.9) | 297(21) | 0(0) | 6822(1.6) | < 0.001 |
Endocrine therapy | 0(0) | 16,839(25.6) | 537(38) | 0(0) | 17,376(4.2) | < 0.001 |
Targeted therapy | 0(0) | 9460(14.4) | 382(27) | 0(0) | 9842(2.4) | < 0.001 |