Table 1 Baseline demographics, cardiovascular disease risk factors, cardiac medication use, and breast cancer characteristics

Age (yrs)

47.0 ± 9.3

White

22 (60%)

ASCVD Risk Factors

Hypertension

13 (35%)

Dyslipidemia

11 (30%)

Diabetes

8 (22%)

Family History

6 (16%)

Current Smoker

3 (8%)

Body Mass Index (kg)

29.6 ± 6.1

Chronic Kidney Disease

0 (0%)

Cardiac Medications

ACE-i/ARB

8 (22%)

Beta-blocker

6 (16%)

Statin

5 (14%)

Aspirin

2 (5%)

Breast Cancer Characteristics

Left-sided

22 (59%)

Stage I

2 (5%)

Stage II

26 (70%)

Stage III

9 (24%)

ER + 

28 (75%)

PR + 

17 (50%)

Treatment Characteristics

DOX dose (mg/m²)

240.0 ± 0.0

Cyclophosphamide Use

37 (100%)

Paclitaxel Use

37 (100%)

Adjuvant radiation

31 (86%)

Baseline Cardiac Markers

GLS

-20.2 ± 2.3%

suPAR (ng/dL)

2.83 (1.31, 3.68)

NT-proBNP (pg/mL)

31.9 (15.3, 90.7)

TnI (ng/dL)

0.01 (0.01, 0.01)

hs-CRP (mg/L)

3.6 (1.7, 10.1)