Skip to main content

Table 2 Primary and secondary endpoints

From: Sodium-glucose co-transporter-2 inhibitors in patients treated with immune checkpoint inhibitors

 

Entire Cohort

Non-SGLT2i

SGLT2i

p value

All-cause Mortality, N (%)

61 (51)

56 (59)

5 (21)

0.002

Progression, N (%)

96 (81)

78 (82)

18 (75)

0.431

MACE, N (%)

16 (13)

12 (13)

4 (17)

0.855

Arrhythmia Composite, N (%)

6 (5)

6 (6)

0 (0)

0.458

Av block, N (%)

1 (1)

1 (1)

0 (0)

1.000

Atrial fibrillation, N (%)

6 (5)

6 (6)

0 (0)

0.458

Acute Coronary Syndrome, N (%)

6 (5)

5 (5)

1 (4)

1.000

Myocarditis, N (%)

2 (2)

2 (2)

0 (0)

1.000

Heart Failure admissions, N (%)

2 (2)

1 (1)

1 (4)

0.864

Heart Failure exacerbations, N (%)

7 (6)

5 (5)

2 (8)

0.932

  1. SGLT2i Sodium-glucose cotransporter 2 inhibitors, N number, MACE Major adverse cardiovascular events