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Table 5 Univariate and multivariate logistic regression analysis for factors associated with CTCRD after 6 months

From: Two-dimensional speckle tracking echocardiography in chemotherapy-induced cardiotoxicity in females with breast cancer

 

Univariate

Multivariate

P-value

Odds ratio (OR)

95% C.I. for OR

P-value

Odds ratio (OR)

95% C.I. for OR

Lower

Upper

Lower

Upper

Diabetes Mellitus

0.000

6.750

2.445

18.637

Trastazumab

0.006

4.241

1.500

11.989

Baseline

 LVESD > 33

0.040

2.857

1.050

7.772

 Diastolic function grade I

0.070

6.815

0.853

54.461

 EF by M-mode <  = 60

0.010

3.710

1.360

10.123

 RV S’ <  = 13

0.073

4.098

0.878

19.123

 GLS % <  = -18

0.001

9.333

2.546

34.214

 GCS % <  = -23.9

0.014

3.385

1.274

8.995

 RVGLS % <  = -22.6

0.018

3.172

1.214

8.288

 RV FWLS % <  = -24

0.040

2.857

1.050

7.772

After 3 months

 LVESD > 33

0.000

10.217

3.128

33.375

 EF M mode <  = 58

0.000

33.889

9.408

122.069

 EF Simpson’s method <  = 55

0.000

82.500

18.904

360.046

 GLS % <  = -15

0.000

85.250

16.803

432.517

 RVGLS % <  = -18

0.000

178.250

21.115

1504.785

 RV FWLS % <  = -19

0.000

207.000

24.136

1775.303

 GLS change <  = 12.5%

0.000

207.000

24.136

1775.303

0.000

198.000

23.046

1701.117

 RVGLS change <  = 21.74%

0.000

198.000

23.046

1701.117

 RVFWLS change <  = 24%

0.000

207.000

24.136

1775.303