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  1. Cardiovascular toxicity is a notorious complication of doxorubicin (DXR) therapy for diffuse large B-cell lymphoma (DLBCL). Although surveillance of well-known biological markers for cardiovascular disease (CV...

    Authors: Charlott Mörth, Amal Abu Sabaa, Eva Freyhult, Christina Christersson, Jamileh Hashemi, Nashmil Hashemi, Masood Kamali-Moghaddam, Daniel Molin, Martin Höglund, Anna Eriksson and Gunilla Enblad
    Citation: Cardio-Oncology 2021 7:6
    Content type: Research Published on:

  2. Craniospinal irradiation (CSI) is part of the treatment of central nervous system (CNS) tumors and is associated with cardiovascular disease in adults. Global myocardial strain analysis including longitudinal ...

    Authors: Hugo R. Martinez, Ralph Salloum, Erin Wright, Lauren Bueche, Philip R. Khoury, Justin T. Tretter and Thomas D. Ryan
    Citation: Cardio-Oncology 2021 7:5
    Content type: Research Published on:

  3. Cancer therapy-related cardiac dysfunction (CTRD) is a major source of morbidity and mortality in long-term cancer survivors. Decreased GLS predicts decreased left ventricular ejection fraction (LVEF) in patie...

    Authors: Raquel Araujo-Gutierrez, Kalyan R. Chitturi, Jiaqiong Xu, Yuanchen Wang, Elizabeth Kinder, Alpana Senapati, L. Bindu Chebrolu, Mahwash Kassi and Barry H. Trachtenberg
    Citation: Cardio-Oncology 2021 7:4
    Content type: Research Published on:

  4. Cardiotoxicity remains a dreaded complication for patients undergoing chemotherapy with human epidermal growth factor (HER)-2 receptor antagonists and anthracyclines. Though many studies have looked at racial ...

    Authors: Crystal B. Chen, Raj K. Dalsania and Eman A. Hamad
    Citation: Cardio-Oncology 2021 7:3
    Content type: Research Published on:

  5. As cardiovascular disease is a leading cause of death in cancer survivors, the new subspecialty of Cardio-Oncology has emerged to address prevention, monitoring, and management of cardiovascular toxicities to ...

    Authors: Sherry-Ann Brown, Sahishnu Patel, David Rayan, Svetlana Zaharova, Mingqian Lin, Tarek Nafee, Bipin Sunkara, Ragasnehith Maddula, James MacLeod, Krishna Doshi, Joshua Meskin, David Marks and Jorge Saucedo
    Citation: Cardio-Oncology 2021 7:2
    Content type: Research Published on:

  7. Anti-neoplastic drugs have made major advancements in oncology, however they are not without cardiovascular consequences. We present a patient with cutaneous T-cell lymphoma receiving Targretin therapy who pre...

    Authors: Sean DeAngelo, Kailyn I. Mann, Muhammad Abdulbasit, Amy Ahnert and Deborah W. Sundlöf
    Citation: Cardio-Oncology 2020 6:31
    Content type: Short communication Published on:

  8. Takotsubo syndrome (TTS), also known as stress cardiomyopathy, apical ballooning syndrome and broken heart syndrome, is characterized by acute-onset chest pain, electrocardiographic (ECG) abnormalities and rev...

    Authors: Aline Cristini Vieira, Mauricio Fernando Silva Almeida Ribeiro, Julianne Lima, Jacob Sessim Filho, Heloisa de Andrade Carvalho and Max Senna Mano
    Citation: Cardio-Oncology 2020 6:30
    Content type: Short communication Published on:

  9. Iron deficiency (ID) and anemia are common in both heart failure (HF) and cancer patients and are associated with poor quality of life and survival. The aims of this study were (1) to evaluate the prevalence, ...

    Authors: E. Čiburienė, J. Čelutkienė, S. Aidietienė, G. Ščerbickaitė and A. R. Lyon
    Citation: Cardio-Oncology 2020 6:29
    Content type: Research Published on:

  10. Re-allocation of resources during the COVID-19 pandemic has resulted in delays in care delivery to patients with cardiovascular disease and cancer. The ability of health care providers to provide optimal care ...

    Authors: Diego Sadler, Jeanne M. DeCara, Joerg Herrmann, Anita Arnold, Arjun K. Ghosh, Husam Abdel-Qadir, Eric H. Yang, Sebastian Szmit, Nausheen Akhter, Monika Leja, Carolina Maria Pinto Domingues Carvalho Silva, Jayant Raikhelkar, Sherry-Ann Brown, Susan Dent, Rupal O’Quinn, Franck Thuny…
    Citation: Cardio-Oncology 2020 6:28
    Content type: Research Published on:

  11. Breast cancer survivors have double the risk of mortality from cardiovascular disease than age-matched women without a cancer history. Reynolds risk score (RRS) is a validated algorithm for the assessment of c...

    Authors: Kyuwan Lee, Nathalie Sami, Debu Tripathy, Wendy Demark-Wahnefried, Mary K. Norris, Kerry S. Courneya and Christina M. Dieli-Conwright
    Citation: Cardio-Oncology 2020 6:27
    Content type: Short communication Published on:

  12. Trastuzumab-induced cardiotoxicity (TIC) can lead to early discontinuation of adjuvant therapy, however there is limited evidence on long-term survival outcomes in patients with operable human epidermal growth...

    Authors: Sagar Sardesai, Jasmine Sukumar, Mahmoud Kassem, Marilly Palettas, Julie Stephens, Evan Morgan, Daniel Addison, Ragavendra Baliga, Daniel G. Stover, Jeffrey VanDeusen, Nicole Williams, Mathew Cherian, Maryam Lustberg, Robert Wesolowski and Bhuvaneswari Ramaswamy
    Citation: Cardio-Oncology 2020 6:26
    Content type: Research Published on:

  13. Sacubitril/Valsartan (S/V) is a novel and remarkably effective opportunity to treat heart failure with reduced ejection fraction (HFrEF). However, patients with HFrEF induced by cancer therapy were a priori ex...

    Authors: Massimiliano Camilli, Marco Giuseppe Del Buono, Pierantonio Menna and Giorgio Minotti
    Citation: Cardio-Oncology 2020 6:25
    Content type: Short communication Published on:

    The original article was published in Cardio-Oncology 2020 6:24

  14. Cancer therapy-related cardiac dysfunction (CTRCD) is a critical problem with an impact on both oncological and cardiovascular prognosis, especially when it prevents patients from receiving cancer treatment. S...

    Authors: Vanesa Gregorietti, Teresa Lopez Fernandez, Diego Costa, Elías Ortega Chahla and Andrés J. Daniele
    Citation: Cardio-Oncology 2020 6:24
    Content type: Research Published on:

    The Short communication to this article has been published in Cardio-Oncology 2020 6:25

  15. Anthracycline-induced cardiac dysfunction (ACD) is a notorious side effect of anticancer treatment. It has been described as a phenomenon of a continuous progressive decline of cardiac function, eventually lea...

    Authors: Janine A. M. Kamphuis, Marijke Linschoten, Maarten J. Cramer, Pieter A. Doevendans, Folkert W. Asselbergs and Arco J. Teske
    Citation: Cardio-Oncology 2020 6:23
    Content type: Research Published on:

  17. Immune checkpoint inhibition is part of standard systemic management for many advanced malignancies. Toxicities from this treatment approach are unpredictable, though usually reversible with management per est...

    Authors: Puja Arora, Laura Talamo, Patrick Dillon, Ryan D. Gentzler, Trish Millard, Michael Salerno, Craig L. Slingluff Jr and Elizabeth M. Gaughan
    Citation: Cardio-Oncology 2020 6:21
    Content type: Research Published on:

  18. An innovative Cardio-Oncology meeting was held in Houston, Texas in January of 2020. This gathering was intended to broaden the scope of Cardio-Oncology to include major presentations by clinicians and researc...

    Authors: Anecita P. Fadol, Nicolas L. Palaskas, Michael S. Ewer and Anita Deswal
    Citation: Cardio-Oncology 2020 6:20
    Content type: Review Published on:

  19. Consideration of heart health for cancer survivors is increasingly important, as improved cancer survivorship has resulted in a growing number of survivors affected by cardiovascular disease. However, there is...

    Authors: Claire C. Conley, Neha G. Goyal and Sherry-Ann Brown
    Citation: Cardio-Oncology 2020 6:19
    Content type: Short communication Published on:

  20. Coronary emboli from malignant tumors rarely cause acute myocardial infarction. We report the case of a patient with tumor embolism from an upper tract urothelial carcinoma that caused acute myocardial infarct...

    Authors: Taku Yasui, Yohei Okuda, Wataru Shioyama, Toru Oka, Tatsuya Nishikawa, Risa Kamada, Koji Hatano, Kazuo Nishimura and Masashi Fujita
    Citation: Cardio-Oncology 2020 6:18
    Content type: Short communication Published on:

  21. Proteasome inhibitors such as carfilzomib are indicated in multiple myeloma patients showing relapse and/or refractoriness of clonal activity. However, this therapy has been associated with a significant incid...

    Authors: Arnold Méndez-Toro, Cándida Díaz-Brochero and Estivalis Acosta-Gutiérrez
    Citation: Cardio-Oncology 2020 6:17
    Content type: Short communication Published on:

  22. In cardio-oncology, a range of clinical dilemmas can be identified where high-quality evidence for management is still lacking. The aim of this project was to study clinical practices and expert approaches to ...

    Authors: E. Hedayati, A. Papakonstantinou, A. Månsson-Broberg, J. Bergh, L. Hubbert and R. Altena
    Citation: Cardio-Oncology 2020 6:16
    Content type: Research Published on:

  23. Hypertension impacts overall prognosis in cancer patients. There are no specific recommendations for its management in these patients. We report a case series of 5 cancer patients with suboptimal BP lowering a...

    Authors: Mishita Goel, Rajiv Sunil Varandani and Tochukwu M. Okwuosa
    Citation: Cardio-Oncology 2020 6:15
    Content type: Short communication Published on:

  24. Various breast cancer (BC) treatments, such as chemotherapy and targeted therapies, increase cardiotoxicity-risk and lead to premature ischemic heart disease and heart failure among survivors. Reducing this ad...

    Authors: Yvonne Koop, Saloua El Messaoudi, Hester Vermeulen, Angela H. E. M. Maas and Femke Atsma
    Citation: Cardio-Oncology 2020 6:14
    Content type: Research Published on:

  25. Adverse cardiac remodeling is an important precursor to anthracycline-related cardiac dysfunction, however conventional remodeling indices are limited. We sought to examine the utility of statistical atlas-der...

    Authors: Hari K. Narayan, Ronghui Xu, Nickolas Forsch, Sachin Govil, David Iukuridze, Lanie Lindenfeld, Eric Adler, Sanjeet Hegde, Adriana Tremoulet, Bonnie Ky, Saro Armenian, Jeffrey Omens and Andrew D. McCulloch
    Citation: Cardio-Oncology 2020 6:13
    Content type: Research Published on:

  26. Radiation-induced coronary artery disease (R-CAD) has become an increasingly recognized phenomenon. Although the clinical relationship between radiation therapy and CAD risk is well known, there is minimal inv...

    Authors: Yaser Khalid, Michael Fradley, Neethi Dasu, Kirti Dasu, Ankit Shah and Adam Levine
    Citation: Cardio-Oncology 2020 6:12
    Content type: Research Published on:

  28. Doxorubicin remains one of the most common causes of cardiotoxicity in patients with lymphoma, leading to significant morbidity and mortality. Early decline in left ventricular (LV) ejection fraction predicts ...

    Authors: Maria Isabel Camara Planek, Ahmad Manshad, Kyaw Hein, Mohamad Hemu, Fatima Ballout, Rajiv Varandani, Parameswaran Venugopal and Tochukwu Okwuosa
    Citation: Cardio-Oncology 2020 6:10
    Content type: Research Published on:

  29. Cardio-Oncology (CO) is a new subspecialty that thrives mostly in large academic quaternary centers. This study describes how to establish a successful cardio-oncology program, with limited resources, in order...

    Authors: Diego Sadler, Chakra Chaulagain, Beatrice Alvarado, Robert Cubeddu, Elizabeth Stone, Thomas Samuel, Bruno Bastos, David Grossman, Chieh-Lin Fu, Evan Alley, Arun Nagarajan, Timmy Nguyen, Wesam Ahmed, Leah Elson and Zeina Nahleh
    Citation: Cardio-Oncology 2020 6:9
    Content type: Research Published on:

  30. Cancer survivors with prior chest radiation therapy (C-XRT) frequently present with aortic stenosis (AS) as the first manifestation of radiation-induced heart disease. They are considered high-risk for surgica...

    Authors: Meer Rabeel Zafar, Syed Farrukh Mustafa, Timothy W. Miller, Talal Alkhawlani and Umesh C. Sharma
    Citation: Cardio-Oncology 2020 6:8
    Content type: Research Published on:

  31. Contrasting to the well documented tyrosine kinase inhibitor (TKI)-induced hypertension, little is known on their intrinsic vasomotor effects. We investigated the vasomotor effects of sorafenib, a widely used ...

    Authors: Hubert Dabiré, Fatou Dramé, Nelly Cita and Bijan Ghaleh
    Citation: Cardio-Oncology 2020 6:7
    Content type: Research Published on:

  32. Radiotherapy has been associated with late dose-dependent cardiovascular toxicity. In this cross-sectional pilot study, radiation dose distributions were correlated with areas of localized and diffuse myocardi...

    Authors: Anthony Ricco, Alexander Slade, Justin M. Canada, John Grizzard, Franklin Dana, Leila Rezai Gharai, Keith Neiderer, Armando Vera, Antonio Abbate and Elisabeth Weiss
    Citation: Cardio-Oncology 2020 6:6
    Content type: Research Published on:

  33. Anthracyclines are a mainstay of chemotherapy. However, a relatively frequent adverse outcome of anthracycline treatment is cardiomyopathy. Multiple genetic studies have begun to dissect the complex genetics u...

    Authors: Timothy N. McOwan, Lauren A. Craig, Anne Tripdayonis, Kathy Karavendzas, Michael M. Cheung, Enzo R. Porrello, Rachel Conyers and David A. Elliott
    Citation: Cardio-Oncology 2020 6:5
    Content type: Research Published on:

  34. High dose melphalan is commonly used as a conditioning regimen for autologous stem cell transplantation in multiple myeloma. There are reports of adverse cardiac events with melphalan manifested by supraventri...

    Authors: Liang-Liang Ma, Ying Liu, Si-Xun Jia, Hai-Chen Lv, Mei-Yun Fang and Yun-Long Xia
    Citation: Cardio-Oncology 2020 6:4
    Content type: Short communication Published on:

  35. Irradiation of the heart during cancer radiotherapy is associated with a dose-dependent risk of heart failure. Animal studies have demonstrated that irradiation leads to an inflammatory response within the hea...

    Authors: Justin M. Canada, Georgia K. Thomas, Cory R. Trankle, Salvatore Carbone, Hayley Billingsley, Benjamin W. Van Tassell, Ronald K. Evans, Ryan Garten, Elisabeth Weiss and Antonio Abbate
    Citation: Cardio-Oncology 2020 6:2
    Content type: Short communication Published on:

  36. Our recent study has revealed that many hospitalized patients with acquired long QT syndrome (ALQTS) are cancer patients. This study aims to determine the risk factors and outcomes of hospitalized cancer patie...

    Authors: Yajuan Lin, Haixu Yu, Fei Liu, Cheng Chen, Yanli Zhang, Binhao Wang, Yiheng Yang, Ying Liu, Li Zhang and Yunlong Xia
    Citation: Cardio-Oncology 2020 6:3
    Content type: Research Published on:

  37. Continuous infusion of doxorubicin or dexrazoxane pre-treatment prior to bolus doxorubicin are proven strategies to protect against doxorubicin-induced cardiotoxicity. Recently, global longitudinal peak systol...

    Authors: Jieli Li, Hui-Ming Chang, Jose Banchs, Dejka M. Araujo, Saamir A. Hassan, Elizabeth A. Wagar, Edward T. H. Yeh and Qing H. Meng
    Citation: Cardio-Oncology 2020 6:1
    Content type: Research Published on:

  38. The lack of a validated symptom assessment instrument in Spanish for patients with cancer and heart failure (HF) can affect the care and impede the recruitment and participation of Spanish-speaking patients in...

    Authors: Anecita Fadol, Joaquin Buitrago, Maria C. Diaz, Valerie Shelton, Carolyn Harty and Tito R. Mendoza
    Citation: Cardio-Oncology 2019 5:19
    Content type: Research Published on:

  39. Cancer diagnostics and therapies have improved steadily over the last few decades, markedly increasing life expectancy for patients at all ages. However, conventional and newer anti-neoplastic therapies can ca...

    Authors: Neha Bansal, M. Jacob Adams, Sarju Ganatra, Steven D. Colan, Sanjeev Aggarwal, Rudolf Steiner, Shahnawaz Amdani, Emma R. Lipshultz and Steven E. Lipshultz
    Citation: Cardio-Oncology 2019 5:18
    Content type: Review Published on:

  40. Takotsubo syndrome (TTS), primarily an acute myocardial inflammatory condition engendered by catecholamine exposure, is associated with similar long-term mortality rates to those of patients with acute myocard...

    Authors: Thanh H. Nguyen, Jeanette Stansborough, Gao J. Ong, Sven Surikow, Timothy J. Price and John D. Horowitz
    Citation: Cardio-Oncology 2019 5:20
    Content type: Research Published on:

  41. Assessment of cardiac function after treatment for breast cancer relies on interval evaluation of ventricular function through echocardiography. Women who undergo mastectomy more frequently choose to undergo b...

    Authors: Joaquin Duarte Ow, Mohamad Hemu, Anel Yakupovich, Parva Bhatt, Hannah Gaddam, Nicole Prabhu, Ibtihaj Fughhi, Melody Cobleigh, Melissa Tracy, Louis Fogg and Tochukwu Okwuosa
    Citation: Cardio-Oncology 2019 5:17
    Content type: Research Published on:

  42. Dexrazoxane protects from lower-cumulative-dose doxorubicin cardiotoxicity, but the effect of dexrazoxane in children with sarcoma treated with higher-cumulative-dose doxorubicin is unknown.

    Authors: Lisa M. Kopp, Richard B. Womer, Cindy L. Schwartz, David H. Ebb, Vivian I. Franco, David Hall, Donald A. Barkauskas, Mark D. Krailo, Holcombe E. Grier, Paul A. Meyers, Leonard H. Wexler, Neyssa M. Marina, Katherine A. Janeway, Richard Gorlick, Mark L. Bernstein and Steven E. Lipshultz
    Citation: Cardio-Oncology 2019 5:15
    Content type: Research Published on:

  43. To enhance the understanding of cardiovascular care delivery in childhood cancer patients and survivors.

    Authors: Thomas D. Ryan, William L. Border, Carissa Baker-Smith, Ana Barac, Matthew J. Bock, Mary M. Canobbio, Nadine F. Choueiter, Devyani Chowdhury, Katheryn E. Gambetta, Julie S. Glickstein, Lavanya Kondapalli, Seema Mital, Vasum Peiris, Russell J. Schiff, Robert L. Spicer, Jeffrey A. Towbin…
    Citation: Cardio-Oncology 2019 5:16
    Content type: Research Published on:

  44. 5-Fluorouracil (5-FU) is an antimetabolite chemotherapy used for a variety of solid tumors. It has the potential to cause a wide spectrum of cardiotoxicity, ranging from asymptomatic electrocardiographic chang...

    Authors: Cai Yuan, Hiral Parekh, Carmen Allegra, Thomas J. George and Jason S. Starr
    Citation: Cardio-Oncology 2019 5:13
    Content type: Review Published on:

  45. Cardio-oncology is a young sub-specialty that addresses the needs of cancer patients at risk of, or who have experienced cancer therapy related cardiac dysfunction (CTRCD). This study assessed clinicians’ unde...

    Authors: J. Peng, M. Rushton, C. Johnson, C. Brezden-Masley, J. Sulpher, Miliyun G. Chiu, I. D. Graham and S. Dent
    Citation: Cardio-Oncology 2019 5:12
    Content type: Research Published on:

  46. Cardiotoxicity is a potential complication of anticancer therapy. While guidelines have been developed to assist practitioners, an effective, evidence based clinical pathway for the treatment of cardiotoxicity...

    Authors: Robyn A. Clark, Tania S. Marin, Alexandra L. McCarthy, Julie Bradley, Suchi Grover, Robyn Peters, Christos S. Karapetis, John J. Atherton and Bogda Koczwara
    Citation: Cardio-Oncology 2019 5:14
    Content type: Research Published on:

  47. Cardiovascular disease (CVD) is the leading non-malignant cause of death in childhood cancer survivors. Heightened risk of CVD is often attributable to treatment with anthracycline chemotherapy. Anthracycline-...

    Authors: Treya M. Long, Channa E. Marsh, Lawrence G. Dembo, Philip Watson, Karen E. Wallman, Thomas S. Walwyn, Catherine S. Choong and Louise H. Naylor
    Citation: Cardio-Oncology 2019 5:11
    Content type: Research Published on:

  48. Early recognition of anthracycline-induced cardiomyopathy may reduce morbidity and mortality in children, but risk stratification tools are lacking. This study evaluates whether electrocardiogram (ECG) changes...

    Authors: Lajja Desai, Lauren Balmert, Jennifer Reichek, Amanda Hauck, Katheryn Gambetta and Gregory Webster
    Citation: Cardio-Oncology 2019 5:10
    Content type: Research Published on:

  49. Improved cancer survival in patients treated with thoracic ionizing radiation (XRT) has resulted in unanticipated surge of aortic stenosis. Transcatheter aortic valve replacement (TAVR) has revolutionized the ...

    Authors: Nikhil Agrawal, Sharma Kattel, Sameer Waheed, Ankita Kapoor, Vasvi Singh, Ashutosh Sharma, Brian J. Page, Kristopher M. Attwood, Vijay Iyer, Saraswati Pokharel and Umesh C. Sharma
    Citation: Cardio-Oncology 2019 5:8
    Content type: Research Published on:

  50. Cardiotoxicity is an adverse effect of trastuzumab (TRA) in the treatment of human epidermal growth factor 2 positive (HER2+) breast cancer. Current literature on the cardioprotective effects of agents targete...

    Authors: Melissa Y. Y. Moey, Darla K. Liles and Blase A. Carabello
    Citation: Cardio-Oncology 2019 5:9
    Content type: Research Published on:
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Cardio-Oncology

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